| Title |
Insufficient maintenance DNA methylation is associated with abnormal embryonic development
|
|---|---|
| Published in |
BMC Medicine, March 2012
|
| DOI | 10.1186/1741-7015-10-26 |
| Pubmed ID | |
| Authors |
Li-Jun Yin, Yu Zhang, Ping-Ping Lv, Wei-Hua He, Yan-Ting Wu, Ai-Xia Liu, Guo-Lian Ding, Min-Yue Dong, Fan Qu, Chen-Ming Xu, Xiao-Ming Zhu, He-Feng Huang |
| Abstract |
Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function of these DNMTs may have serious consequences for embryonic development. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 29% |
| United States | 1 | 14% |
| Netherlands | 1 | 14% |
| Mexico | 1 | 14% |
| Unknown | 2 | 29% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 5 | 71% |
| Members of the public | 2 | 29% |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 69 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 19% |
| Student > Master | 11 | 16% |
| Student > Bachelor | 8 | 11% |
| Researcher | 8 | 11% |
| Student > Doctoral Student | 4 | 6% |
| Other | 7 | 10% |
| Unknown | 19 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 14 | 20% |
| Agricultural and Biological Sciences | 13 | 19% |
| Medicine and Dentistry | 13 | 19% |
| Psychology | 2 | 3% |
| Environmental Science | 1 | 1% |
| Other | 5 | 7% |
| Unknown | 22 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2012.
All research outputs
#2,807,279
of 24,172,513 outputs
Outputs from BMC Medicine
#1,741
of 3,694 outputs
Outputs of similar age
#16,877
of 159,849 outputs
Outputs of similar age from BMC Medicine
#15
of 34 outputs
Altmetric has tracked 24,172,513 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,694 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.3. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 159,849 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.