| Title |
Microneedles: A New Frontier in Nanomedicine Delivery
|
|---|---|
| Published in |
Pharmaceutical Research, February 2016
|
| DOI | 10.1007/s11095-016-1885-5 |
| Pubmed ID | |
| Authors |
Eneko Larrañeta, Maelíosa T. C. McCrudden, Aaron J. Courtenay, Ryan F. Donnelly |
| Abstract |
This review aims to concisely chart the development of two individual research fields, namely nanomedicines, with specific emphasis on nanoparticles (NP) and microparticles (MP), and microneedle (MN) technologies, which have, in the recent past, been exploited in combinatorial approaches for the efficient delivery of a variety of medicinal agents across the skin. This is an emerging and exciting area of pharmaceutical sciences research within the remit of transdermal drug delivery and as such will undoubtedly continue to grow with the emergence of new formulation and fabrication methodologies for particles and MN. Firstly, the fundamental aspects of skin architecture and structure are outlined, with particular reference to their influence on NP and MP penetration. Following on from this, a variety of different particles are described, as are the diverse range of MN modalities currently under development. The review concludes by highlighting some of the novel delivery systems which have been described in the literature exploiting these two approaches and directs the reader towards emerging uses for nanomedicines in combination with MN. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 361 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | <1% |
| United States | 2 | <1% |
| Ireland | 1 | <1% |
| Romania | 1 | <1% |
| Unknown | 354 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 73 | 20% |
| Researcher | 45 | 12% |
| Student > Master | 43 | 12% |
| Student > Bachelor | 36 | 10% |
| Student > Doctoral Student | 17 | 5% |
| Other | 46 | 13% |
| Unknown | 101 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 79 | 22% |
| Engineering | 36 | 10% |
| Chemistry | 34 | 9% |
| Agricultural and Biological Sciences | 22 | 6% |
| Materials Science | 18 | 5% |
| Other | 59 | 16% |
| Unknown | 113 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2022.
All research outputs
#1,599,628
of 24,273,038 outputs
Outputs from Pharmaceutical Research
#48
of 2,937 outputs
Outputs of similar age
#26,446
of 303,384 outputs
Outputs of similar age from Pharmaceutical Research
#2
of 40 outputs
Altmetric has tracked 24,273,038 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,937 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.