| Title |
Recent advances in the determination of tocopherols in biological fluids: from sample pretreatment and liquid chromatography to clinical studies
|
|---|---|
| Published in |
Analytical & Bioanalytical Chemistry, January 2016
|
| DOI | 10.1007/s00216-015-9214-0 |
| Pubmed ID | |
| Authors |
Barbora Cervinkova, Lenka Kujovska Krcmova, Dagmar Solichova, Bohuslav Melichar, Petr Solich |
| Abstract |
Vitamin E comprises eight related compounds: α-, β-, γ-, δ-tocopherols and α-, β-, γ-, δ-tocotrienols. In the past, α-tocopherol has been the isomer that was studied most, and its anti-inflammatory and anti-proliferative effects have been described. Therefore, many prevention trials have investigated the effect of α-tocopherol on human health. Current research studies have also defined the important roles of other tocopherols, such as anti-inflammatory, anti-proliferative and cancer preventative effects. Knowledge of the individual tocopherols could help to understand their roles in various metabolic pathways. This review summarizes the recent trends in sample pretreatment, liquid chromatography and selected applications of the determination of tocopherols in various biological materials. The relationship between tocopherol isomers and serious diseases is also described. Graphical Abstract Article structure. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 23 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 6 | 26% |
| Student > Ph. D. Student | 3 | 13% |
| Student > Doctoral Student | 2 | 9% |
| Student > Bachelor | 2 | 9% |
| Student > Master | 2 | 9% |
| Other | 5 | 22% |
| Unknown | 3 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 8 | 35% |
| Agricultural and Biological Sciences | 3 | 13% |
| Arts and Humanities | 1 | 4% |
| Unspecified | 1 | 4% |
| Medicine and Dentistry | 1 | 4% |
| Other | 1 | 4% |
| Unknown | 8 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2016.
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#22,759,802
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Outputs from Analytical & Bioanalytical Chemistry
#7,542
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Outputs of similar age
#343,320
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Outputs of similar age from Analytical & Bioanalytical Chemistry
#68
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