| Title |
Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF)
|
|---|---|
| Published in |
Osteoporosis International, August 2019
|
| DOI | 10.1007/s00198-019-05104-5 |
| Pubmed ID | |
| Authors |
M. Hiligsmann, D. Cornelissen, B. Vrijens, B. Abrahamsen, N. Al-Daghri, E. Biver, M.L. Brandi, O. Bruyère, N. Burlet, C. Cooper, B. Cortet, E. Dennison, A. Diez-Perez, A. Gasparik, A. Grosso, P. Hadji, P. Halbout, J.A. Kanis, J.M. Kaufman, A. Laslop, S. Maggi, R. Rizzoli, T. Thomas, S. Tuzun, M. Vlaskovska, J.Y. Reginster |
| Abstract |
Many patients at increased risk of fractures do not take their medication appropriately, resulting in a substantial decrease in the benefits of drug therapy. Improving medication adherence is urgently needed but remains laborious, given the numerous and multidimensional reasons for non-adherence, suggesting the need for measurement-guided, multifactorial and individualized solutions. Poor adherence to medications is a major challenge in the treatment of osteoporosis. This paper aimed to provide an overview of the consequences, determinants and potential solutions to poor adherence and persistence to osteoporosis medication. A working group was organized by the European Society on Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal diseases (ESCEO) to review consequences, determinants and potential solutions to adherence and to make recommendations for practice and further research. A systematic literature review and a face-to-face experts meeting were undertaken. Medication non-adherence is associated with increased risk of fractures, leading to a substantial decrease in the clinical and economic benefits of drug therapy. Reasons for non-adherence are numerous and multidimensional for each patient, depending on the interplay of multiple factors, suggesting the need for multifactorial and individualized solutions. Few interventions have been shown to improve adherence or persistence to osteoporosis treatment. Promising actions include patient education with counselling, adherence monitoring with feedback and dose simplification including flexible dosing regimen. Recommendations for practice and further research were also provided. To adequately manage adherence, it is important to (1) understand the problem (initiation, implementation and/or persistence), (2) to measure adherence and (3) to identify the reason of non-adherence and fix it. These recommendations are intended for clinicians to manage adherence of their patients and to researchers and policy makers to design, facilitate and appropriately use adherence interventions. |
X Demographics
The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 3 | 18% |
| Spain | 2 | 12% |
| United States | 1 | 6% |
| United Kingdom | 1 | 6% |
| Switzerland | 1 | 6% |
| Poland | 1 | 6% |
| Chile | 1 | 6% |
| Brazil | 1 | 6% |
| Australia | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 4 | 24% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 53% |
| Scientists | 5 | 29% |
| Practitioners (doctors, other healthcare professionals) | 2 | 12% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 132 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 132 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 12% |
| Student > Ph. D. Student | 14 | 11% |
| Student > Bachelor | 12 | 9% |
| Student > Master | 10 | 8% |
| Student > Doctoral Student | 9 | 7% |
| Other | 25 | 19% |
| Unknown | 46 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 30 | 23% |
| Nursing and Health Professions | 8 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Psychology | 6 | 5% |
| Social Sciences | 5 | 4% |
| Other | 21 | 16% |
| Unknown | 55 | 42% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2021.
All research outputs
#2,532,689
of 25,163,621 outputs
Outputs from Osteoporosis International
#411
of 3,841 outputs
Outputs of similar age
#50,382
of 351,040 outputs
Outputs of similar age from Osteoporosis International
#7
of 77 outputs
Altmetric has tracked 25,163,621 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,841 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one has done well, scoring higher than 89% of its peers.
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We're also able to compare this research output to 77 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.