| Title |
Severe drug eruptions revisited
|
|---|---|
| Published in |
Immunologic Research, March 2012
|
| DOI | 10.1007/s12026-012-8271-0 |
| Pubmed ID | |
| Authors |
Sebastien Calbo |
| Abstract |
Genetic and non-genetic factors can alter the action of a medicinal drug, resulting in a wide range of responses in different individuals. Among the many potential side effects of therapies, a drug eruption is an adverse drug reaction in the skin. Genetic associations between HLA haplotype and drug eruption have been reported, and immune responses against latent herpesvirus have also been implicated in some forms of this syndrome. We believe that it is essential to understand the immune mechanisms by which some drugs induce hypersensitivity so that we can better target these pathways to limit drug side effects. The identification of patient risk factors for drug eruptions will allow the rational design of novel immunotherapies for these life-threatening reactions, and the development of alternative interventions for high-risk patients. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 10 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Doctoral Student | 1 | 10% |
| Student > Ph. D. Student | 1 | 10% |
| Student > Master | 1 | 10% |
| Researcher | 1 | 10% |
| Professor > Associate Professor | 1 | 10% |
| Other | 1 | 10% |
| Unknown | 4 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 20% |
| Computer Science | 1 | 10% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 10% |
| Immunology and Microbiology | 1 | 10% |
| Chemistry | 1 | 10% |
| Other | 0 | 0% |
| Unknown | 4 | 40% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2012.
All research outputs
#15,242,707
of 22,663,969 outputs
Outputs from Immunologic Research
#557
of 904 outputs
Outputs of similar age
#99,645
of 155,896 outputs
Outputs of similar age from Immunologic Research
#22
of 27 outputs
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