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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The major autolysin is redundant for Staphylococcus aureus USA300 LAC JE2 virulence in a murine device-related infection model.
|
|---|---|
| Published in |
FEMS Microbiology Letters, April 2016
|
| DOI | 10.1093/femsle/fnw087 |
| Pubmed ID | |
| Authors |
Hannah McCarthy, Elaine M Waters, Jeffrey L Bose, Simon Foster, Kenneth W Bayles, Eoghan O'Neill, Paul D Fey, James P O'Gara |
| Abstract |
The majorStaphylococcus aureusautolysin, Atl, has been implicated in attachment to surfaces and release of extracellular DNA during biofilm formation under laboratory conditions. Consistent with this, polyclonal antibodies to the amidase (AM) and glucosaminidase (GL) domains of Atl inhibitedin vitrobiofilm formation. However, in a murine model of device-related infection the community-associatedS. aureusstrain USA300 LAC JE2 established a successful infection in the absence ofatl These data indicate that Atl activity is not required for biofilm production in this infection model and reveal the importance of characterising the contribution of biofilm phenotypes to virulence underin vivoconditions. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 32 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 7 | 22% |
| Researcher | 4 | 13% |
| Student > Postgraduate | 4 | 13% |
| Student > Master | 3 | 9% |
| Student > Doctoral Student | 3 | 9% |
| Other | 4 | 13% |
| Unknown | 7 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 8 | 25% |
| Biochemistry, Genetics and Molecular Biology | 7 | 22% |
| Immunology and Microbiology | 3 | 9% |
| Nursing and Health Professions | 2 | 6% |
| Computer Science | 1 | 3% |
| Other | 3 | 9% |
| Unknown | 8 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2016.
All research outputs
#22,760,732
of 25,377,790 outputs
Outputs from FEMS Microbiology Letters
#5,488
of 5,773 outputs
Outputs of similar age
#272,257
of 315,146 outputs
Outputs of similar age from FEMS Microbiology Letters
#43
of 51 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,773 research outputs from this source. They receive a mean Attention Score of 4.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,146 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.