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Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol

Overview of attention for article published in BMJ Open, April 2016
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Title
Effects of exercise intensity and nutrition advice on myocardial function in obese children and adolescents: a multicentre randomised controlled trial study protocol
Published in
BMJ Open, April 2016
DOI 10.1136/bmjopen-2015-010929
Pubmed ID
Authors

Katrin A Dias, Jeff S Coombes, Daniel J Green, Sjaan R Gomersall, Shelley E Keating, Arnt Erik Tjonna, Siri Marte Hollekim-Strand, Mansoureh Sadat Hosseini, Torstein Baade Ro, Margrete Haram, Else Marie Huuse, Peter S W Davies, Peter A Cain, Gary M Leong, Charlotte B Ingul

Abstract

The prevalence of paediatric obesity is increasing, and with it, lifestyle-related diseases in children and adolescents. High-intensity interval training (HIIT) has recently been explored as an alternate to traditional moderate-intensity continuous training (MICT) in adults with chronic disease and has been shown to induce a rapid reversal of subclinical disease markers in obese children and adolescents. The primary aim of this study is to compare the effects of HIIT with MICT on myocardial function in obese children and adolescents. Multicentre randomised controlled trial of 100 obese children and adolescents in the cities of Trondheim (Norway) and Brisbane (Australia). The trial will examine the efficacy of HIIT to improve cardiometabolic outcomes in obese children and adolescents. Participants will be randomised to (1) HIIT and nutrition advice, (2) MICT and nutrition advice or (3) nutrition advice. Participants will partake in supervised exercise training and/or nutrition sessions for 3 months. Measurements for study end points will occur at baseline, 3 months (postintervention) and 12 months (follow-up). The primary end point is myocardial function (peak systolic tissue velocity). Secondary end points include vascular function (flow-mediated dilation assessment), quantity of visceral and subcutaneous adipose tissue, myocardial structure and function, body composition, cardiorespiratory fitness, autonomic function, blood biochemistry, physical activity and nutrition. Lean, healthy children and adolescents will complete measurements for all study end points at one time point for comparative cross-sectional analyses. This randomised controlled trial will generate substantial information regarding the effects of exercise intensity on paediatric obesity, specifically the cardiometabolic health of this at-risk population. It is expected that communication of results will allow for the development of more effective evidence-based exercise prescription guidelines in this population while investigating the benefits of HIIT on subclinical markers of disease. NCT01991106.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 322 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
Unknown 321 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 58 18%
Student > Bachelor 46 14%
Student > Ph. D. Student 24 7%
Student > Doctoral Student 24 7%
Researcher 19 6%
Other 50 16%
Unknown 101 31%
Readers by discipline Count As %
Sports and Recreations 58 18%
Nursing and Health Professions 52 16%
Medicine and Dentistry 49 15%
Biochemistry, Genetics and Molecular Biology 11 3%
Social Sciences 6 2%
Other 32 10%
Unknown 114 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2016.
All research outputs
#20,656,161
of 25,373,627 outputs
Outputs from BMJ Open
#21,929
of 25,587 outputs
Outputs of similar age
#234,532
of 314,637 outputs
Outputs of similar age from BMJ Open
#351
of 396 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 25,587 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 7th percentile – i.e., 7% of its peers scored the same or lower than it.
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