Title |
Biosensing made easy with PEG-targeted bi-specific antibodies
|
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Published in |
Chemical Communications, January 2016
|
DOI | 10.1039/c6cc01916a |
Pubmed ID | |
Authors |
Lyndon J. Raftery, Yadveer S. Grewal, Christopher B. Howard, Martina L. Jones, Muhammad J. A. Shiddiky, Laura G. Carrascosa, Kristofer J. Thurecht, Stephen M. Mahler, Matt Trau |
Abstract |
Whilst recent advances in nanotechnology have yielded many new biosensing capabilities, innovative biological attachment and detection modalities remain relatively underdeveloped. Bi-specific antibodies (bsAbs) - which exhibit binding capability for two separate targets - offer an inherent advantage over conventional antibody reagents by significantly simplifying sensor surface preparation. Herein, we report the deployment of bsAbs for simultaneous attachment to a polymer-coated transducer and label-free, electrochemical (EC) detection of target antigens. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 43% |
Researcher | 3 | 14% |
Student > Bachelor | 2 | 10% |
Professor | 1 | 5% |
Unknown | 6 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 5 | 24% |
Chemical Engineering | 3 | 14% |
Engineering | 2 | 10% |
Agricultural and Biological Sciences | 1 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Other | 2 | 10% |
Unknown | 7 | 33% |