Title |
Does quantification of myocardial flow reserve using rubidium-82 positron emission tomography facilitate detection of multivessel coronary artery disease?
|
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Published in |
Journal of Nuclear Cardiology, March 2012
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DOI | 10.1007/s12350-011-9506-5 |
Pubmed ID | |
Authors |
Maria C. Ziadi, Robert A. deKemp, Kathryn Williams, Ann Guo, Jennifer M. Renaud, Benjamin J.W. Chow, Ran Klein, Terrence D. Ruddy, May Aung, Linda Garrard, Rob S.B. Beanlands |
Abstract |
Relative myocardial perfusion imaging (MPI) is the standard imaging approach for the diagnosis and prognostic work-up of coronary artery disease (CAD). However, this technique may underestimate the extent of disease in patients with 3-vessel CAD. Positron emission tomography (PET) is also able to quantify myocardial blood flow. Rubidium-82 ((82)Rb) is a valid PET tracer alternative in centers that lack a cyclotron. The aim of this study was to assess whether assessment of myocardial flow reserve (MFR) measured with (82)Rb PET is an independent predictor of severe obstructive 3-vessel CAD. |
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