| Title |
Diagnosis and treatment of diabetic ketoacidosis and the hyperglycemic hyperosmolar state.
|
|---|---|
| Published in |
Canadian Medical Association Journal, April 2003
|
| Pubmed ID | |
| Authors |
Jean-Louis Chiasson, Nahla Aris-Jilwan, Raphaël Bélanger, Sylvie Bertrand, Hugues Beauregard, Jean-Marie Ekoé, Hélène Fournier, Jana Havrankova |
| Abstract |
Diabetic ketoacidosis and the hyperglycemic hyperosmolar state are the most serious complications of diabetic decompensation and remain associated with excess mortality. Insulin deficiency is the main underlying abnormality. Associated with elevated levels of counterregulatory hormones, insulin deficiency can trigger hepatic glucose production and reduced glucose uptake, resulting in hyperglycemia, and can also stimulate lipolysis and ketogenesis, resulting in ketoacidosis. Both hyperglycemia and hyperketonemia will induce osmotic diuresis, which leads to dehydration. Clinical diagnosis is based on the finding of dehydration along with high capillary glucose levels with or without ketones in the urine or plasma. The diagnosis is confirmed by the blood pH, serum bicarbonate level and serum osmolality. Treatment consists of adequate correction of the dehydration, hyperglycemia, ketoacidosis and electrolyte deficits. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 526 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 4 | <1% |
| Brazil | 2 | <1% |
| United Kingdom | 2 | <1% |
| Italy | 1 | <1% |
| Macao | 1 | <1% |
| India | 1 | <1% |
| Switzerland | 1 | <1% |
| Germany | 1 | <1% |
| Poland | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 512 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 123 | 23% |
| Student > Postgraduate | 81 | 15% |
| Other | 59 | 11% |
| Student > Master | 44 | 8% |
| Researcher | 37 | 7% |
| Other | 95 | 18% |
| Unknown | 87 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 267 | 51% |
| Agricultural and Biological Sciences | 34 | 6% |
| Nursing and Health Professions | 32 | 6% |
| Biochemistry, Genetics and Molecular Biology | 31 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 25 | 5% |
| Other | 39 | 7% |
| Unknown | 98 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2020.
All research outputs
#3,621,150
of 25,743,152 outputs
Outputs from Canadian Medical Association Journal
#3,497
of 9,541 outputs
Outputs of similar age
#5,575
of 63,820 outputs
Outputs of similar age from Canadian Medical Association Journal
#11
of 45 outputs
Altmetric has tracked 25,743,152 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 34.1. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 63,820 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.