Title |
Genetic variation study of 12 X chromosomal STR in central Thailand population
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Published in |
International Journal of Legal Medicine, April 2016
|
DOI | 10.1007/s00414-016-1363-y |
Pubmed ID | |
Authors |
Kornkiat Vongpaisarnsin, Achara Boonlert, Kawin Rasmeepaisarn, Piyawan Dangkao |
Abstract |
Genetic data from 12 short tandem repeats (STR) on the X chromosome are currently used in forensics studies to resolve issues related to complex kinship or when data is missing or ambiguous. In this study, we genotyped these 12 X chromosome STR in DNA collected from individuals from central Thailand (n = 391, 282 men and 109 women) and used this information to calculate allele and haplotype frequencies as well as forensic parameters for kinship calculations. Polymorphism information contents of the loci were range from 0.5283-0.9247, and powers of discrimination in females and males were 0.7666-0.9905 and 0.6085-0.9291, respectively. A diallelic pattern was observed at the locus DXS7132. Moreover, a comparison of genetic distance revealed a close relationship within Asian countries. Our results indicate that the X chromosomal short tandem repeat (X-STR) multiplex system provides highly informative genetic data and could be advantageous in forensic studies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 18 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 4 | 22% |
Student > Master | 2 | 11% |
Unspecified | 1 | 6% |
Student > Ph. D. Student | 1 | 6% |
Professor > Associate Professor | 1 | 6% |
Other | 1 | 6% |
Unknown | 8 | 44% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 7 | 39% |
Agricultural and Biological Sciences | 2 | 11% |
Unspecified | 1 | 6% |
Medicine and Dentistry | 1 | 6% |
Unknown | 7 | 39% |