| Title |
Autoantibodies and High-Risk HLA Susceptibility Markers in First-Degree Relatives of Brazilian Patients with Type 1 Diabetes Mellitus: A Progression to Disease Based Study
|
|---|---|
| Published in |
Journal of Clinical Immunology, March 2012
|
| DOI | 10.1007/s10875-012-9673-4 |
| Pubmed ID | |
| Authors |
L. I. Alves, E. Davini, M. R. Correia, R. T. Fukui, R. F. Santos, M. R. Cunha, D. M. Rocha, W. M. G. Volpini, M. E. R. Silva |
| Abstract |
The objective of this study was to determine the frequencies of autoantibodies to heterogeneous islet-cell cytoplasmic antigens (ICA), glutamic acid decarboxylase(65) (GAD(65)A), insulinoma-associated antigen-2 (IA-2A) and insulin (IAA)-and human leukocyte antigen (HLA) class II markers (HLA-DR and -DQ) in first degree relatives of heterogeneous Brazilian patients with type I diabetes (T1DM). A major focus of this study was to determine the influence of age, gender, proband characteristics and ancestry on the prevalence of autoantibodies and HLA-DR and -DQ alleles on disease progression and genetic predisposition to T1DM among the first-degree relatives. |
Mendeley readers
The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 23 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 30% |
| Student > Master | 3 | 13% |
| Student > Ph. D. Student | 3 | 13% |
| Librarian | 2 | 9% |
| Lecturer | 1 | 4% |
| Other | 2 | 9% |
| Unknown | 5 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 35% |
| Agricultural and Biological Sciences | 2 | 9% |
| Social Sciences | 2 | 9% |
| Business, Management and Accounting | 1 | 4% |
| Immunology and Microbiology | 1 | 4% |
| Other | 3 | 13% |
| Unknown | 6 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2012.
All research outputs
#20,156,138
of 22,663,969 outputs
Outputs from Journal of Clinical Immunology
#1,250
of 1,556 outputs
Outputs of similar age
#141,606
of 156,320 outputs
Outputs of similar age from Journal of Clinical Immunology
#12
of 14 outputs
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