Title |
Cortico-cerebellar functional connectivity and sequencing of movements in schizophrenia
|
---|---|
Published in |
BMC Psychiatry, March 2012
|
DOI | 10.1186/1471-244x-12-17 |
Pubmed ID | |
Authors |
Tomas Kasparek, Jitka Rehulova, Milos Kerkovsky, Andrea Sprlakova, Marek Mechl, Michal Mikl |
Abstract |
Abnormal execution of several movements in a sequence is a frequent finding in schizophrenia. Successful performance of such motor acts requires correct integration of cortico-subcortical processes, particularly those related to cerebellar functions. Abnormal connectivity between cortical and cerebellar regions with resulting cognitive dysmetria has been proposed as the core dysfunction behind many signs and symptoms of schizophrenia. The aim of the present study was to assess if these proposed abnormalities in connectivity are a unifying feature of schizophrenia, or, rather, reflect a specific symptom domain of a heterogeneous disease. We predicted that abnormal functional connectivity between the motor cortex and cerebellum would be linked with abnormal performance of movement sequencing. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Egypt | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Uruguay | 1 | 1% |
Unknown | 66 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 14 | 21% |
Researcher | 12 | 18% |
Student > Ph. D. Student | 11 | 16% |
Student > Bachelor | 6 | 9% |
Other | 5 | 7% |
Other | 10 | 15% |
Unknown | 10 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 14 | 21% |
Medicine and Dentistry | 13 | 19% |
Neuroscience | 10 | 15% |
Nursing and Health Professions | 4 | 6% |
Agricultural and Biological Sciences | 4 | 6% |
Other | 8 | 12% |
Unknown | 15 | 22% |