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Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults

Overview of attention for article published in British Journal of Nutrition, April 2016
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Title
Serum 25-hydroxyvitamin D concentrations and cardiometabolic risk factors in adolescents and young adults
Published in
British Journal of Nutrition, April 2016
DOI 10.1017/s0007114516001185
Pubmed ID
Authors

Lucinda J. Black, Sally Burrows, Robyn M. Lucas, Carina E. Marshall, Rae-Chi Huang, Wendy Chan She Ping-Delfos, Lawrence J. Beilin, Patrick G. Holt, Prue H. Hart, Wendy H. Oddy, Trevor A. Mori

Abstract

Evidence associating serum 25-hydroxyvitamin D (25(OH)D) concentrations and cardiometabolic risk factors is inconsistent and studies have largely been conducted in adult populations. We examined the prospective associations between serum 25(OH)D concentrations and cardiometabolic risk factors from adolescence to young adulthood in the West Australian Pregnancy Cohort (Raine) Study. Serum 25(OH)D concentrations, BMI, homoeostasis model assessment for insulin resistance (HOMA-IR), TAG, HDL-cholesterol and systolic blood pressure (SBP) were measured at the 17-year (n 1015) and 20-year (n 1117) follow-ups. Hierarchical linear mixed models with maximum likelihood estimation were used to investigate associations between serum 25(OH)D concentrations and cardiometabolic risk factors, accounting for potential confounders. In males and females, respectively, mean serum 25(OH)D concentrations were 73·6 (sd 28·2) and 75·4 (sd 25·9) nmol/l at 17 years and 70·0 (sd 24·2) and 74·3 (sd 26·2) nmol/l at 20 years. Deseasonalised serum 25(OH)D3 concentrations were inversely associated with BMI (coefficient -0·01; 95 % CI -0·03, -0·003; P=0·014). No change over time was detected in the association for males; for females, the inverse association was stronger at 20 years compared with 17 years. Serum 25(OH)D concentrations were inversely associated with log-HOMA-IR (coefficient -0·002; 95 % CI -0·003, -0·001; P<0·001) and positively associated with log-TAG in females (coefficient 0·002; 95 % CI 0·0008, 0·004; P=0·003). These associations did not vary over time. There were no significant associations between serum 25(OH)D concentrations and HDL-cholesterol or SBP. Clinical trials in those with insufficient vitamin D status may be warranted to determine any beneficial effect of vitamin D supplementation on insulin resistance, while monitoring for any deleterious effect on TAG.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 65 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 17%
Researcher 6 9%
Student > Doctoral Student 4 6%
Student > Bachelor 4 6%
Other 3 5%
Other 9 14%
Unknown 28 43%
Readers by discipline Count As %
Medicine and Dentistry 16 25%
Nursing and Health Professions 6 9%
Sports and Recreations 3 5%
Agricultural and Biological Sciences 2 3%
Immunology and Microbiology 1 2%
Other 3 5%
Unknown 34 52%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2016.
All research outputs
#17,302,400
of 25,394,764 outputs
Outputs from British Journal of Nutrition
#4,883
of 6,279 outputs
Outputs of similar age
#193,976
of 315,593 outputs
Outputs of similar age from British Journal of Nutrition
#83
of 115 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,279 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 19.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,593 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.