Title |
The Heavy Burden of Psychiatric Comorbidity in Youth with Autism Spectrum Disorders: A Large Comparative Study of a Psychiatrically Referred Population
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Published in |
Journal of Autism and Developmental Disorders, March 2010
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DOI | 10.1007/s10803-010-0996-9 |
Pubmed ID | |
Authors |
Gagan Joshi, Carter Petty, Janet Wozniak, Aude Henin, Ronna Fried, Maribel Galdo, Meghan Kotarski, Sarah Walls, Joseph Biederman |
Abstract |
The objective of the study was to systematically examine patterns of psychiatric comorbidity in referred youth with autism spectrum disorders (ASD) including autistic disorder and pervasive developmental disorder not otherwise specified. Consecutively referred children and adolescents to a pediatric psychopharmacology program were assessed with structured diagnostic interview and measures of psychosocial functioning. Comparisons were made between those youth satisfying diagnostic criteria for ASD and age and sex matched youth without ASD referred to the same clinical program. 9.3% (217/2323) of the referred youth (age range: 3-17 years) met DSM-III-R criteria for ASD. ASD youth suffered from significantly higher number of comorbid disorders than comparisons (6.4 ± 2.7 vs. 5.2 ± 2.9; p < 0.001). Ninety-five percent of the youth with ASD had three or more comorbid psychiatric disorders and 74% had five or more comorbid disorders. ASD youth were also more functionally impaired and required extra-assistance in school and therapeutic interventions at higher rates than age and sex matched non-ASD referred youth. Youth with ASD have high levels of psychiatric comorbidity and dysfunction comparable to the referred population of youth without ASD. These findings emphasize the heavy burden of psychiatric comorbidity afflicting youth with ASD and may be important targets for intervention. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | <1% |
United States | 2 | <1% |
Netherlands | 1 | <1% |
Unknown | 330 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 60 | 18% |
Student > Ph. D. Student | 41 | 12% |
Student > Doctoral Student | 36 | 11% |
Researcher | 34 | 10% |
Student > Bachelor | 27 | 8% |
Other | 58 | 17% |
Unknown | 79 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 124 | 37% |
Medicine and Dentistry | 40 | 12% |
Neuroscience | 15 | 4% |
Nursing and Health Professions | 14 | 4% |
Agricultural and Biological Sciences | 12 | 4% |
Other | 34 | 10% |
Unknown | 96 | 29% |