| Title |
Regulation of bile acid metabolism-related signaling pathways by gut microbiota in diseases
|
|---|---|
| Published in |
Journal of Zhejiang University - Science B, September 2019
|
| DOI | 10.1631/jzus.b1900073 |
| Pubmed ID | |
| Authors |
Er-teng Jia, Zhi-yu Liu, Min Pan, Jia-feng Lu, Qin-yu Ge |
| Abstract |
Over the past decade, there has been increasing attention on the interaction between microbiota and bile acid metabolism. Bile acids are not only involved in the metabolism of nutrients, but are also important in signal transduction for the regulation of host physiological activities. Microbial-regulated bile acid metabolism has been proven to affect many diseases, but there have not been many studies of disease regulation by microbial receptor signaling pathways. This review considers findings of recent research on the core roles of farnesoid X receptor (FXR), G protein-coupled bile acid receptor (TGR5), and vitamin D receptor (VDR) signaling pathways in microbial-host interactions in health and disease. Studying the relationship between these pathways can help us understand the pathogenesis of human diseases, and lead to new solutions for their treatments. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 41 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 6 | 15% |
| Student > Bachelor | 4 | 10% |
| Other | 3 | 7% |
| Student > Doctoral Student | 2 | 5% |
| Student > Postgraduate | 2 | 5% |
| Other | 6 | 15% |
| Unknown | 18 | 44% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 7 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
| Nursing and Health Professions | 3 | 7% |
| Medicine and Dentistry | 3 | 7% |
| Agricultural and Biological Sciences | 3 | 7% |
| Other | 4 | 10% |
| Unknown | 18 | 44% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2019.
All research outputs
#22,771,990
of 25,385,509 outputs
Outputs from Journal of Zhejiang University - Science B
#555
of 704 outputs
Outputs of similar age
#302,489
of 351,548 outputs
Outputs of similar age from Journal of Zhejiang University - Science B
#3
of 7 outputs
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So far Altmetric has tracked 704 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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