| Title |
Potential Role of the Microbiome in Barrett’s Esophagus and Esophageal Adenocarcinoma
|
|---|---|
| Published in |
Digestive Diseases and Sciences, April 2016
|
| DOI | 10.1007/s10620-016-4155-9 |
| Pubmed ID | |
| Authors |
Erik J. Snider, Daniel E. Freedberg, Julian A. Abrams |
| Abstract |
Esophageal adenocarcinoma and its precursor Barrett's esophagus have been rapidly increasing in incidence for half a century, for reasons not adequately explained by currently identified risk factors such as gastroesophageal reflux disease and obesity. The upper gastrointestinal microbiome may represent another potential cofactor. The distal esophagus has a distinct microbiome of predominantly oral-derived flora, which is altered in Barrett's esophagus and reflux esophagitis. Chronic low-grade inflammation or direct carcinogenesis from this altered microbiome may combine with known risk factors to promote Barrett's metaplasia and progression to adenocarcinoma. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 106 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 106 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 14% |
| Researcher | 13 | 12% |
| Student > Ph. D. Student | 11 | 10% |
| Other | 9 | 8% |
| Student > Doctoral Student | 8 | 8% |
| Other | 21 | 20% |
| Unknown | 29 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 31 | 29% |
| Biochemistry, Genetics and Molecular Biology | 11 | 10% |
| Agricultural and Biological Sciences | 10 | 9% |
| Nursing and Health Professions | 6 | 6% |
| Chemistry | 5 | 5% |
| Other | 7 | 7% |
| Unknown | 36 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 June 2023.
All research outputs
#2,548,610
of 23,989,432 outputs
Outputs from Digestive Diseases and Sciences
#283
of 4,464 outputs
Outputs of similar age
#41,589
of 304,549 outputs
Outputs of similar age from Digestive Diseases and Sciences
#2
of 53 outputs
Altmetric has tracked 23,989,432 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,464 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 304,549 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.