Title |
Evolution of the metabolic and regulatory networks associated with oxygen availability in two phytopathogenic enterobacteria
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Published in |
BMC Genomics, March 2012
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DOI | 10.1186/1471-2164-13-110 |
Pubmed ID | |
Authors |
Lavanya Babujee, Jennifer Apodaca, Venkatesh Balakrishnan, Paul Liss, Patricia J Kiley, Amy O Charkowski, Jeremy D Glasner, Nicole T Perna |
Abstract |
Dickeya dadantii and Pectobacterium atrosepticum are phytopathogenic enterobacteria capable of facultative anaerobic growth in a wide range of O2 concentrations found in plant and natural environments. The transcriptional response to O2 remains under-explored for these and other phytopathogenic enterobacteria although it has been well characterized for animal-associated genera including Escherichia coli and Salmonella enterica. Knowledge of the extent of conservation of the transcriptional response across orthologous genes in more distantly related species is useful to identify rates and patterns of regulon evolution. Evolutionary events such as loss and acquisition of genes by lateral transfer events along each evolutionary branch results in lineage-specific genes, some of which may have been subsequently incorporated into the O2-responsive stimulon. Here we present a comparison of transcriptional profiles measured using densely tiled oligonucleotide arrays for two phytopathogens, Dickeya dadantii 3937 and Pectobacterium atrosepticum SCRI1043, grown to mid-log phase in MOPS minimal medium (0.1% glucose) with and without O2. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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United Kingdom | 1 | 1% |
United States | 1 | 1% |
Unknown | 69 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 14 | 20% |
Student > Ph. D. Student | 11 | 15% |
Student > Bachelor | 7 | 10% |
Student > Postgraduate | 6 | 8% |
Student > Master | 6 | 8% |
Other | 9 | 13% |
Unknown | 18 | 25% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 29 | 41% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Chemistry | 3 | 4% |
Environmental Science | 2 | 3% |
Computer Science | 2 | 3% |
Other | 9 | 13% |
Unknown | 18 | 25% |