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Molecular epidemiology of Mycobacterium abscessus complex isolates in Ireland

Overview of attention for article published in Journal of Cystic Fibrosis, June 2015
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Title
Molecular epidemiology of Mycobacterium abscessus complex isolates in Ireland
Published in
Journal of Cystic Fibrosis, June 2015
DOI 10.1016/j.jcf.2015.05.007
Pubmed ID
Authors

C. O'Driscoll, J. Konjek, B. Heym, M.M. Fitzgibbon, B.J. Plant, M. Ní Chróinín, D. Mullane, M. Lynch-Healy, G.D. Corcoran, K. Schaffer, T.R. Rogers, M.B. Prentice

Abstract

The Mycobacterium abscessus complex are the rapidly growing mycobacteria (RGM) most commonly causing lung disease, especially in cystic fibrosis (CF) patients. Ireland has the world's highest CF incidence. The molecular epidemiology of M. abscessus complex in Ireland is unreported. We performed rpoB gene sequencing and multi-locus sequence typing (MLST) on M. abscessus complex strains isolated from thirty-six patients in 2006-2012 (eighteen known CF patients). Twenty-eight strains (78%) were M. abscessus subsp. abscessus, eight M. abscessus subsp. massiliense, none were M. abscessus subsp. bolletii. Sequence type 1 (ST1) and ST26 (M. abscessus subsp. abscessus) were commonest. Seven M. abscessus subsp. abscessus STs (25%) were novel (two with novel alleles). Seven M. abscessus subsp. massiliense STs were previously reported (88%), including two ST23, the globally successful clone. In 2012, of 552 CF patients screened, eleven were infected with M. abscessus complex strains (2%). The most prevalent M. abscessus subsp. abscessus and M. abscessus subsp. massiliense strains in Ireland belong to widely-distributed STs, but there is evidence of high M. abscessus subsp. abscessus diversity.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 35 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 17%
Student > Master 5 14%
Student > Ph. D. Student 4 11%
Other 3 9%
Student > Doctoral Student 3 9%
Other 5 14%
Unknown 9 26%
Readers by discipline Count As %
Immunology and Microbiology 9 26%
Biochemistry, Genetics and Molecular Biology 6 17%
Medicine and Dentistry 5 14%
Agricultural and Biological Sciences 3 9%
Unknown 12 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 January 2017.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Journal of Cystic Fibrosis
#1,786
of 2,111 outputs
Outputs of similar age
#238,883
of 279,879 outputs
Outputs of similar age from Journal of Cystic Fibrosis
#111
of 115 outputs
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