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The relationship between CYP2C19 polymorphisms and ischaemic and bleeding outcomes in stable outpatients: the CHARISMA genetics study

Overview of attention for article published in European Heart Journal, March 2012
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Title
The relationship between CYP2C19 polymorphisms and ischaemic and bleeding outcomes in stable outpatients: the CHARISMA genetics study
Published in
European Heart Journal, March 2012
DOI 10.1093/eurheartj/ehs059
Pubmed ID
Authors

Deepak L. Bhatt, Guillaume Paré, John W. Eikelboom, Katy L. Simonsen, Eileen S. Emison, Keith A.A. Fox, Ph. Gabriel Steg, Gilles Montalescot, Nihar Bhakta, Werner Hacke, Marcus D. Flather, Koon-Hou Mak, Patrice Cacoub, Mark A. Creager, Peter B. Berger, Steven R. Steinhubl, Gurunathan Murugesan, Shamir R. Mehta, Kandice Kottke-Marchant, A. Michael Lincoff, Eric J. Topol

Abstract

Clinical trials have established the value of clopidogrel therapy in a wide spectrum of patients with cardiovascular diseases. Both loss- and gain-of-function single nucleotide variants of CYP2C19 genes have been identified that affect clopidogrel metabolism and anti-platelet response. We sought to determine the impact of CYP2C19 polymorphisms on ischaemic and bleeding events.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
Sweden 1 1%
Singapore 1 1%
Canada 1 1%
Unknown 79 95%

Demographic breakdown

Readers by professional status Count As %
Other 11 13%
Student > Bachelor 11 13%
Student > Ph. D. Student 8 10%
Researcher 8 10%
Student > Postgraduate 7 8%
Other 20 24%
Unknown 18 22%
Readers by discipline Count As %
Medicine and Dentistry 37 45%
Pharmacology, Toxicology and Pharmaceutical Science 8 10%
Nursing and Health Professions 4 5%
Biochemistry, Genetics and Molecular Biology 3 4%
Agricultural and Biological Sciences 2 2%
Other 3 4%
Unknown 26 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 March 2013.
All research outputs
#17,656,184
of 22,663,969 outputs
Outputs from European Heart Journal
#8,255
of 9,913 outputs
Outputs of similar age
#120,030
of 160,299 outputs
Outputs of similar age from European Heart Journal
#53
of 75 outputs
Altmetric has tracked 22,663,969 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,913 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.6. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,299 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.