| Title |
Effects of an Oral Elemental Nutritional Supplement on Post-gastrectomy Body Weight Loss in Gastric Cancer Patients: A Randomized Controlled Clinical Trial
|
|---|---|
| Published in |
Annals of Surgical Oncology, April 2016
|
| DOI | 10.1245/s10434-016-5221-4 |
| Pubmed ID | |
| Authors |
Hiroshi Imamura, Kazuhiro Nishikawa, Kentaro Kishi, Kentaro Inoue, Jin Matsuyama, Yusuke Akamaru, Yutaka Kimura, Shigeyuki Tamura, Ryohei Kawabata, Junji Kawada, Yoshiyuki Fujiwara, Tomono Kawase, Junichi Fukui, Mari Takagi, Atsushi Takeno, Toshio Shimokawa |
| Abstract |
Post-gastrectomy weight loss is associated with deterioration in quality of life, and influences the long-term prognosis of gastric cancer patients. We conducted a prospective, randomized controlled, open-label study to examine whether an oral elemental diet (Elental(®), Ajinomoto Pharmaceuticals, Tokyo, Japan; hereafter referred to as ED) prevents postoperative weight loss in post-gastrectomy patients. Patients were randomly divided to receive the ED or control diet. The ED group received 300 kcal of ED plus their regular diet for 6-8 weeks after surgery, starting from the day the patient started a soft rice or equivalent diet after surgery, while the control group received the regular diet alone. The primary endpoint was the percentage of body weight loss (%BWL) from the presurgical body weight to that at 6-8 weeks after surgery. Secondary endpoints were dietary adherence, nutrition-related blood parameters, and adverse events. This study included 112 patients in eight hospitals. The mean treatment compliance rate in the ED group was 68.7 ± 30.4 % (median 81.2 %). The %BWL was significantly different between the ED and control groups (4.86 ± 3.72 vs. 6.60 ± 4.90 %, respectively; p = 0.047). In patients who underwent total gastrectomy, the %BWL was significantly different between the two groups (5.03 ± 3.65 vs. 9.13 ± 5.43 %, respectively; p = 0.012). In multivariate analysis, ED treatment, surgery type, and preoperative performance status were independently associated with %BWL. No significant differences were observed in the other clinical variables. ED supplementation reduced postoperative weight loss in gastric cancer patients undergoing gastrectomy. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 113 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 113 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 15 | 13% |
| Researcher | 11 | 10% |
| Student > Ph. D. Student | 9 | 8% |
| Student > Master | 8 | 7% |
| Student > Doctoral Student | 8 | 7% |
| Other | 24 | 21% |
| Unknown | 38 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 32 | 28% |
| Nursing and Health Professions | 15 | 13% |
| Sports and Recreations | 6 | 5% |
| Biochemistry, Genetics and Molecular Biology | 5 | 4% |
| Psychology | 4 | 4% |
| Other | 11 | 10% |
| Unknown | 40 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2018.
All research outputs
#7,233,951
of 22,862,742 outputs
Outputs from Annals of Surgical Oncology
#2,499
of 6,480 outputs
Outputs of similar age
#102,488
of 299,054 outputs
Outputs of similar age from Annals of Surgical Oncology
#35
of 101 outputs
Altmetric has tracked 22,862,742 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 6,480 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,054 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.