Title |
Angiotensin Receptor Blockers and Tumorigenesis: Something To Be (or Not To Be) Concerned About?
|
---|---|
Published in |
Current Hypertension Reports, April 2012
|
DOI | 10.1007/s11906-012-0263-x |
Pubmed ID | |
Authors |
Vadim Tchaikovski, Gregory Y. H. Lip |
Abstract |
The possibility of carcinogenic side effects of antihypertensive therapies due to their chronic administration has been raised multiple times in the past. Recently, the issue has again drawn attention, this time in relation to angiotensin receptor blockers (ARBs). This, among others, caused both American and European drug regulation authorities to review the underlying evidence concerning the relationship between this class of medications and potential adverse carcinogenic outcome. A plethora of both basic science and preclinical evidence has been generated, and three meta-analyses and one nationwide cohort have focused on this specific question. The current review aims to summarize the contemporary multidisciplinary evidence on whether ARBs may be associated with an increased risk of tumorigenesis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Korea, Republic of | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 6% |
Unknown | 16 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 18% |
Student > Ph. D. Student | 2 | 12% |
Researcher | 2 | 12% |
Professor | 1 | 6% |
Librarian | 1 | 6% |
Other | 2 | 12% |
Unknown | 6 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 7 | 41% |
Agricultural and Biological Sciences | 2 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
Unknown | 7 | 41% |