| Title |
Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans
|
|---|---|
| Published in |
Food Science and Biotechnology, April 2016
|
| DOI | 10.1007/s10068-016-0076-9 |
| Pubmed ID | |
| Authors |
Atsushi Yamatsu, Yusuke Yamashita, Tukaram Pandharipande, Isafumi Maru, Mujo Kim |
| Abstract |
The effects of γ-aminobutyric acid (GABA) on sleep and its levels in blood after oral administration were investigated in humans. A randomized, single-blind, placebo-controlled crossover-designed study was conducted to evaluate the effect of GABA on sleep. Sleep was evaluated by electroencephalography (EEG) after oral GABA administration. GABA significantly shortened sleep latency and increased the total non-rapid eye movement (non-REM) sleep time. Questionnaires showed that subjects receiving GABA realized its effects on sleep. In addition, the blood level of GABA after administration was investigated, and the absorption and metabolism rates of GABA were determined. GABA was quickly absorbed, and the blood level of GABA was the highest 30 min after oral administration, with a subsequent decrease in concentration. As GABA strongly affected the early stage of sleep, the effect of GABA on sleep may be connected to its levels in blood. |
X Demographics
The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | 14% |
| Japan | 1 | 14% |
| United States | 1 | 14% |
| Unknown | 4 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 109 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 11% |
| Student > Ph. D. Student | 11 | 10% |
| Student > Bachelor | 10 | 9% |
| Student > Master | 10 | 9% |
| Other | 8 | 7% |
| Other | 12 | 11% |
| Unknown | 46 | 42% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 13 | 12% |
| Medicine and Dentistry | 11 | 10% |
| Biochemistry, Genetics and Molecular Biology | 7 | 6% |
| Nursing and Health Professions | 4 | 4% |
| Immunology and Microbiology | 4 | 4% |
| Other | 18 | 17% |
| Unknown | 52 | 48% |
Attention Score in Context
This research output has an Altmetric Attention Score of 256. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2024.
All research outputs
#146,094
of 25,756,531 outputs
Outputs from Food Science and Biotechnology
#3
of 549 outputs
Outputs of similar age
#2,668
of 313,050 outputs
Outputs of similar age from Food Science and Biotechnology
#1
of 10 outputs
Altmetric has tracked 25,756,531 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 549 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,050 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them