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Mendeley readers
Attention Score in Context
| Title |
Graphene/quantum dot bionanoconjugates as signal amplifiers in stripping voltammetric detection of EpCAM biomarkers
|
|---|---|
| Published in |
Biosensors & Bioelectronics, March 2012
|
| DOI | 10.1016/j.bios.2012.02.057 |
| Pubmed ID | |
| Authors |
Muhammad J.A. Shiddiky, Sakandar Rauf, Prakash H. Kithva, Matt Trau |
| Abstract |
A sensitive electrochemical immunosensor for the detection of epithelial cell adhesion molecule (EpCAM) antigen, a common marker for tumors of epithelial origin, employing bionanoconjugates as signal-transduction labels has been developed. The bionanoconjugates were fabricated by carboxylation of the two-dimensional graphene oxide nanosheets (GRs) and immobilizing streptavidin and amine-functionalized CdSe quantum dots (QDs) on carboxylated GRs via carbodiimide coupling chemistry, followed by the immunoreaction with the biotinylated secondary antibodies. Since carboxylated GRs have a higher density of active sites, it allows a large number of CdSe QDs to be immobilized onto the surface of the bionanoconjugates, and hence, enhance the sensitivity of the immunosensor. The method enabled detection limits of 100 fg/mL and 1 pg/mL (based on the S/N=3) in PBS buffer and serum samples, respectively, using anodic stripping voltammetric readout. The immunosensor showed a good selectivity, reproducibility, and long-storage stability, and may become a promising technique for the early detection of tumor biomarker in clinical/biological samples. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 2% |
| India | 1 | 2% |
| France | 1 | 2% |
| Argentina | 1 | 2% |
| Unknown | 55 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 29% |
| Student > Master | 8 | 14% |
| Researcher | 7 | 12% |
| Professor > Associate Professor | 3 | 5% |
| Student > Bachelor | 3 | 5% |
| Other | 10 | 17% |
| Unknown | 11 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 17 | 29% |
| Materials Science | 8 | 14% |
| Agricultural and Biological Sciences | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Engineering | 4 | 7% |
| Other | 8 | 14% |
| Unknown | 12 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2012.
All research outputs
#20,674,485
of 25,394,764 outputs
Outputs from Biosensors & Bioelectronics
#5,421
of 6,858 outputs
Outputs of similar age
#132,420
of 169,125 outputs
Outputs of similar age from Biosensors & Bioelectronics
#42
of 48 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,858 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,125 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.