Title |
Review article: Part two: Goal‐directed resuscitation – Which goals? Perfusion targets
|
---|---|
Published in |
Emergency Medicine Australasia, January 2012
|
DOI | 10.1111/j.1742-6723.2011.01515.x |
Pubmed ID | |
Authors |
Anthony Holley, William Lukin, Jennifer Paratz, Tracey Hawkins, Robert Boots, Jeffrey Lipman |
Abstract |
Haemodynamic targets, such as cardiac output, mean arterial blood pressure and central venous oxygen saturations, remain crude predictors of tissue perfusion and oxygen supply at a cellular level. Shocked patients may appear adequately resuscitated based on normalization of global vital signs, yet they are still experiencing occult hypoperfusion. If targeted resuscitation is employed, appropriate use of end-points is critical. In this review, we consider the value of directing resuscitation at the microcirculation or cellular level. Current technologies available include sublingual capnometry, video microscopy of the microcirculation and near-infrared spectroscopy providing a measure of tissue oxygenation, whereas base deficit and lactate potentially provide a surrogate measure of the adequacy of global perfusion. The methodology and evidence for these technologies guiding resuscitation are considered in this narrative review. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
New Zealand | 1 | 50% |
United Kingdom | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Germany | 1 | 2% |
Unknown | 60 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 13 | 21% |
Other | 10 | 16% |
Professor | 8 | 13% |
Student > Master | 7 | 11% |
Researcher | 6 | 10% |
Other | 11 | 18% |
Unknown | 7 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 42 | 68% |
Nursing and Health Professions | 2 | 3% |
Business, Management and Accounting | 1 | 2% |
Computer Science | 1 | 2% |
Environmental Science | 1 | 2% |
Other | 4 | 6% |
Unknown | 11 | 18% |