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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Genotypic and Phenotypic Markers of Livestock-Associated Methicillin-Resistant Staphylococcus aureus CC9 in Humans
|
|---|---|
| Published in |
Applied and Environmental Microbiology, June 2016
|
| DOI | 10.1128/aem.00091-16 |
| Pubmed ID | |
| Authors |
Xiaohua Ye, Xiaolin Wang, Yanping Fan, Yang Peng, Ling Li, Shunming Li, Jingya Huang, Zhenjiang Yao, Sidong Chen |
| Abstract |
Use of antimicrobials in industrial food-animal production is associated with the presence of multidrug-resistant Staphylococcus aureus (S. aureus) among animals and humans. The livestock-associated (LA) methicillin-resistant S. aureus (MRSA) CC9 is found related to animals and related workers in Asia. This study aimed to explore the genotypic and phenotypic markers of LA-MRSA CC9 in humans. We conducted a cross-sectional study of livestock workers and controls in Guangdong, China. The study participants responded to a questionnaire and provided a nasal swab for S.aureus analysis. Resulting isolates were assessed for antibiotic susceptibility, multilocus sequence type, and immune evasion cluster (IEC) genes. Livestock workers had significantly higher rates of S. aureus CC9 (OR = 30.98, 95% CI 4.06-236.39) and tetracycline-resistant S. aureus (OR = 3.26, 95% CI 2.12-5.00) than controls. All 19 S. aureus CC9 from livestock workers were MRSA isolates and also exhibited the characteristics of resistance to several classes of antibiotics and absence of the IEC genes. Notably, the interaction analyses indicated phenotype-phenotype (OR=525.7, 95% CI: 60.0- 4602.1) and gene-environment (OR=232.3, 95% CI 28.7-1876.7) interactions associated with increased risk for livestock-associated S. aureus CC9 carriage. These findings suggest that livestock-associated S. aureus and MRSA (CC9, IEC-negative, tetracycline-resistant) in humans are associated with occupational livestock contact, raising questions about the potential for occupational exposure to opportunistic S. aureus IMPORTANCE: This study adds to existing knowledge by giving insight into the genotypic and phenotypic markers of LA-MRSA. Our findings suggest that livestock-associated S. aureus and MRSA (CC9, IEC-negative, tetracycline-resistant) in humans are associated with occupational livestock contact. Future studies should direct more attention to exploring the exact transmission routes and establishing measures to prevent the spread of LA-MRSA. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 78 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 15% |
| Researcher | 11 | 14% |
| Student > Doctoral Student | 9 | 12% |
| Student > Master | 8 | 10% |
| Student > Bachelor | 7 | 9% |
| Other | 14 | 18% |
| Unknown | 17 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 15% |
| Medicine and Dentistry | 11 | 14% |
| Immunology and Microbiology | 10 | 13% |
| Veterinary Science and Veterinary Medicine | 9 | 12% |
| Environmental Science | 7 | 9% |
| Other | 9 | 12% |
| Unknown | 20 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2016.
All research outputs
#17,289,387
of 25,377,790 outputs
Outputs from Applied and Environmental Microbiology
#16,648
of 19,163 outputs
Outputs of similar age
#237,413
of 368,504 outputs
Outputs of similar age from Applied and Environmental Microbiology
#111
of 167 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 19,163 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one is in the 8th percentile – i.e., 8% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,504 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.