Title |
High Prevalence of Respiratory Ciliary Dysfunction in Congenital Heart Disease Patients With Heterotaxy
|
---|---|
Published in |
Circulation, April 2012
|
DOI | 10.1161/circulationaha.111.079780 |
Pubmed ID | |
Authors |
Nader Nakhleh, Richard Francis, Rachel A. Giese, Xin Tian, You Li, Maimoona A. Zariwala, Hisato Yagi, Omar Khalifa, Safina Kureshi, Bishwanath Chatterjee, Steven L. Sabol, Matthew Swisher, Patricia S. Connelly, Mathew P. Daniels, Ashok Srinivasan, Karen Kuehl, Nadav Kravitz, Kimberlie Burns, Iman Sami, Heymut Omran, Michael Barmada, Kenneth Olivier, Kunal K. Chawla, Margaret Leigh, Richard Jonas, Michael Knowles, Linda Leatherbury, Cecilia W. Lo |
Abstract |
Patients with congenital heart disease (CHD) and heterotaxy show high postsurgical morbidity/mortality, with some developing respiratory complications. Although this finding is often attributed to the CHD, airway clearance and left-right patterning both require motile cilia function. Thus, airway ciliary dysfunction (CD) similar to that of primary ciliary dyskinesia (PCD) may contribute to increased respiratory complications in heterotaxy patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 50% |
Argentina | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
United States | 1 | <1% |
Portugal | 1 | <1% |
Unknown | 106 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 19 | 17% |
Student > Ph. D. Student | 13 | 12% |
Other | 11 | 10% |
Student > Doctoral Student | 8 | 7% |
Professor | 8 | 7% |
Other | 24 | 22% |
Unknown | 26 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 46 | 42% |
Agricultural and Biological Sciences | 16 | 15% |
Biochemistry, Genetics and Molecular Biology | 12 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | <1% |
Nursing and Health Professions | 1 | <1% |
Other | 6 | 6% |
Unknown | 27 | 25% |