| Title |
Negative symptoms and their association with depressive symptoms in the long-term course of schizophrenia
|
|---|---|
| Published in |
European Archives of Psychiatry and Clinical Neuroscience, April 2016
|
| DOI | 10.1007/s00406-016-0697-2 |
| Pubmed ID | |
| Authors |
Wolfram an der Heiden, Anne Leber, Heinz Häfner |
| Abstract |
Depressive symptoms abound in schizophrenia and even in subclinical states of the disorder. We studied the frequency of these symptoms and their relationship to negative symptoms from the first psychotic episode on over a long-term course of 134 months on data for 107 patients in our ABC Schizophrenia Study. Prevalence rates of 90 % for presenting at least one negative symptom and of 60 % for presenting at least one depressive symptom in the first psychotic episode illustrate the frequency of these syndromes. After the remission of psychosis the rates fell to 50 % (negative symptoms) and 40 % (depressive symptoms) over a period of 5 years, remaining stable thereafter. After we broke the negative syndrome down into (SANS) subsyndromes, a positive association emerged between anhedonia and depressive symptoms and remained stable over the entire period studied. In contrast, the association between abulia and depression grew increasingly pronounced over the illness course. However, a more detailed look revealed this to be the case in female patients only, whereas male patients showed no such association of these symptom dimensions. We have no explanation at hand for this sex difference yet. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 115 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 16 | 14% |
| Student > Ph. D. Student | 12 | 10% |
| Student > Bachelor | 12 | 10% |
| Student > Postgraduate | 10 | 9% |
| Student > Doctoral Student | 9 | 8% |
| Other | 17 | 15% |
| Unknown | 39 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 25 | 22% |
| Medicine and Dentistry | 18 | 16% |
| Neuroscience | 12 | 10% |
| Agricultural and Biological Sciences | 2 | 2% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 9 | 8% |
| Unknown | 47 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2016.
All research outputs
#21,164,509
of 23,815,455 outputs
Outputs from European Archives of Psychiatry and Clinical Neuroscience
#1,094
of 1,243 outputs
Outputs of similar age
#255,767
of 300,903 outputs
Outputs of similar age from European Archives of Psychiatry and Clinical Neuroscience
#11
of 13 outputs
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