| Title |
The new heterologous fibrin sealant in combination with low-level laser therapy (LLLT) in the repair of the buccal branch of the facial nerve
|
|---|---|
| Published in |
Lasers in Medical Science, April 2016
|
| DOI | 10.1007/s10103-016-1939-2 |
| Pubmed ID | |
| Authors |
Daniela Vieira Buchaim, Antonio de Castro Rodrigues, Rogerio Leone Buchaim, Benedito Barraviera, Rui Seabra Ferreira Junior, Geraldo Marco Rosa Junior, Cleuber Rodrigo de Souza Bueno, Domingos Donizeti Roque, Daniel Ventura Dias, Leticia Rossi Dare, Jesus Carlos Andreo |
| Abstract |
This study aimed to evaluate the effects of low-level laser therapy (LLLT) in the repair of the buccal branch of the facial nerve with two surgical techniques: end-to-end epineural suture and coaptation with heterologous fibrin sealant. Forty-two male Wistar rats were randomly divided into five groups: control group (CG) in which the buccal branch of the facial nerve was collected without injury; (2) experimental group with suture (EGS) and experimental group with fibrin (EGF): The buccal branch of the facial nerve was transected on both sides of the face. End-to-end suture was performed on the right side and fibrin sealant on the left side; (3) Experimental group with suture and laser (EGSL) and experimental group with fibrin and laser (EGFL). All animals underwent the same surgical procedures in the EGS and EGF groups, in combination with the application of LLLT (wavelength of 830 nm, 30 mW optical power output of potency, and energy density of 6 J/cm(2)). The animals of the five groups were euthanized at 5 weeks post-surgery and 10 weeks post-surgery. Axonal sprouting was observed in the distal stump of the facial nerve in all experimental groups. The observed morphology was similar to the fibers of the control group, with a predominance of myelinated fibers. In the final period of the experiment, the EGSL presented the closest results to the CG, in all variables measured, except in the axon area. Both surgical techniques analyzed were effective in the treatment of peripheral nerve injuries, where the use of fibrin sealant allowed the manipulation of the nerve stumps without trauma. LLLT exhibited satisfactory results on facial nerve regeneration, being therefore a useful technique to stimulate axonal regeneration process. |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 49 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 9 | 18% |
| Student > Doctoral Student | 6 | 12% |
| Student > Ph. D. Student | 5 | 10% |
| Professor | 3 | 6% |
| Student > Master | 3 | 6% |
| Other | 8 | 16% |
| Unknown | 15 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 31% |
| Nursing and Health Professions | 4 | 8% |
| Agricultural and Biological Sciences | 2 | 4% |
| Materials Science | 2 | 4% |
| Neuroscience | 2 | 4% |
| Other | 7 | 14% |
| Unknown | 17 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 April 2016.
All research outputs
#20,322,106
of 22,865,319 outputs
Outputs from Lasers in Medical Science
#1,076
of 1,309 outputs
Outputs of similar age
#252,924
of 298,657 outputs
Outputs of similar age from Lasers in Medical Science
#27
of 31 outputs
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