| Title |
General lack of global dosage compensation in ZZ/ZW systems? Broadening the perspective with RNA-seq
|
|---|---|
| Published in |
BMC Genomics, February 2011
|
| DOI | 10.1186/1471-2164-12-91 |
| Pubmed ID | |
| Authors |
Jochen BW Wolf, Jarosław Bryk |
| Abstract |
Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose. Microarray-based studies in several independent male heterogametic XX/XY systems suggest that dosage compensation mechanisms are in place to mitigate the detrimental effects of gene dose differences. However, recent genomic research on female heterogametic ZZ/ZW systems has generated surprising results. In two bird species and one lepidopteran no evidence for a global dosage compensating mechanism has been found. The recent advent of massively parallel RNA sequencing now opens up the possibility to gauge the generality of this observation with a broader phylogenetic sampling. It further allows assessing the validity of microarray-based inference on dosage compensation with a novel technology. |
Mendeley readers
The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 4% |
| Sweden | 3 | 3% |
| Netherlands | 2 | 2% |
| Switzerland | 1 | <1% |
| Unknown | 101 | 91% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 29% |
| Researcher | 25 | 23% |
| Student > Master | 19 | 17% |
| Student > Bachelor | 11 | 10% |
| Professor > Associate Professor | 5 | 5% |
| Other | 12 | 11% |
| Unknown | 7 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 68 | 61% |
| Biochemistry, Genetics and Molecular Biology | 23 | 21% |
| Business, Management and Accounting | 2 | 2% |
| Medicine and Dentistry | 2 | 2% |
| Computer Science | 2 | 2% |
| Other | 4 | 4% |
| Unknown | 10 | 9% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2017.
All research outputs
#6,378,788
of 22,664,267 outputs
Outputs from BMC Genomics
#2,864
of 10,614 outputs
Outputs of similar age
#46,967
of 182,372 outputs
Outputs of similar age from BMC Genomics
#22
of 75 outputs
Altmetric has tracked 22,664,267 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 10,614 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 182,372 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.