| Title |
Association between nutritional status and dengue infection: a systematic review and meta-analysis
|
|---|---|
| Published in |
BMC Infectious Diseases, April 2016
|
| DOI | 10.1186/s12879-016-1498-y |
| Pubmed ID | |
| Authors |
Nguyen Thi Huyen Trang, Nguyen Phuoc Long, Tran Thi Minh Hue, Le Phi Hung, Tran Dinh Trung, Doan Ngoc Dinh, Nguyen Thien Luan, Nguyen Tien Huy, Kenji Hirayama |
| Abstract |
Dengue infection has various clinical manifestations, often with unpredictable clinical evolutions and outcomes. Several factors including nutritional status have been studied to find the relationship with dengue severity. However, the nutritional status had conflicting effects on the complication of dengue in some previous studies. Therefore, we conducted a systematic review and performed a meta-analysis to analyze the association between nutritional status and the outcome of dengue infection. Eleven electronic databases and manual searching of reference lists were used to identify the relevant studies published before August 2013. At least two authors worked independently in every step to select eligible studies and extract data. Dengue severity in the included studies must be classified into three categories: dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). Thirteen articles that met the inclusion criteria came to final analysis. A meta-analysis using fixed- or random-effects models was conducted to calculate pooled odds ratios (OR) with corresponding 95 % confidence intervals. It has shown that there was no statistically significant association between DHF group and DSS group in malnutritional and overweight/obesity patients with OR: 1.17 (95 % CI: 0.99-1.39), 1.31 (0.91-1.88), respectively. A significantly inverse relation between DF and DHF groups of malnutritional patients was revealed (OR = 0.71, 95 % CI: 0.56-0.90). Our meta-analysis also indicated a statistically significant negative correlation between malnourished children with dengue virus infection and healthy children (OR = 0.46, 95 % CI: 0.3-0.70). When analyzing patients with normal nutrition status, we found out that there was a significantly negative relationship between DHF and DSS groups (0.87; 95 % CI: 0.77-0.99). Other comparisons of DSS with DF/DHF groups, DSS/DHF with DF groups, and DHF with DF groups in normal nutritional patients showed no significant correlation. However, the findings should be interpreted cautiously because all significant associations were lost after removing of the largest study. Results from previous studies failed to show any solid consistency regarding the association between the nutritional status and dengue infection. Consequently, the effects of nutritional status on dengue disease outcome has been controversial. Further studies are recommended to clarify the impact of nutritional status on dengue infection. |
Mendeley readers
The data shown below were compiled from readership statistics for 193 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 193 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 37 | 19% |
| Student > Bachelor | 23 | 12% |
| Researcher | 16 | 8% |
| Student > Postgraduate | 11 | 6% |
| Other | 10 | 5% |
| Other | 23 | 12% |
| Unknown | 73 | 38% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 54 | 28% |
| Nursing and Health Professions | 17 | 9% |
| Biochemistry, Genetics and Molecular Biology | 12 | 6% |
| Immunology and Microbiology | 12 | 6% |
| Agricultural and Biological Sciences | 9 | 5% |
| Other | 14 | 7% |
| Unknown | 75 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2017.
All research outputs
#13,232,464
of 22,865,319 outputs
Outputs from BMC Infectious Diseases
#3,173
of 7,687 outputs
Outputs of similar age
#142,164
of 299,366 outputs
Outputs of similar age from BMC Infectious Diseases
#52
of 112 outputs
Altmetric has tracked 22,865,319 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,687 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has gotten more attention than average, scoring higher than 57% of its peers.
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We're also able to compare this research output to 112 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.