| Title |
Burkholderia: an update on taxonomy and biotechnological potential as antibiotic producers
|
|---|---|
| Published in |
Applied Microbiology and Biotechnology, April 2016
|
| DOI | 10.1007/s00253-016-7520-x |
| Pubmed ID | |
| Authors |
Eliza Depoorter, Matt J. Bull, Charlotte Peeters, Tom Coenye, Peter Vandamme, Eshwar Mahenthiralingam |
| Abstract |
Burkholderia is an incredibly diverse and versatile Gram-negative genus, within which over 80 species have been formally named and multiple other genotypic groups likely represent new species. Phylogenetic analysis based on the 16S rRNA gene sequence and core genome ribosomal multilocus sequence typing analysis indicates the presence of at least three major clades within the genus. Biotechnologically, Burkholderia are well-known for their bioremediation and biopesticidal properties. Within this review, we explore the ability of Burkholderia to synthesise a wide range of antimicrobial compounds ranging from historically characterised antifungals to recently described antibacterial antibiotics with activity against multiresistant clinical pathogens. The production of multiple Burkholderia antibiotics is controlled by quorum sensing and examples of quorum sensing pathways found across the genus are discussed. The capacity for antibiotic biosynthesis and secondary metabolism encoded within Burkholderia genomes is also evaluated. Overall, Burkholderia demonstrate significant biotechnological potential as a source of novel antibiotics and bioactive secondary metabolites. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 274 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Sweden | 1 | <1% |
| Germany | 1 | <1% |
| Belgium | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 270 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 45 | 16% |
| Student > Master | 43 | 16% |
| Student > Bachelor | 40 | 15% |
| Researcher | 29 | 11% |
| Student > Doctoral Student | 27 | 10% |
| Other | 26 | 9% |
| Unknown | 64 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 82 | 30% |
| Biochemistry, Genetics and Molecular Biology | 66 | 24% |
| Immunology and Microbiology | 23 | 8% |
| Environmental Science | 8 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 3% |
| Other | 18 | 7% |
| Unknown | 70 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 June 2021.
All research outputs
#4,446,017
of 24,119,703 outputs
Outputs from Applied Microbiology and Biotechnology
#1,086
of 8,034 outputs
Outputs of similar age
#66,258
of 303,190 outputs
Outputs of similar age from Applied Microbiology and Biotechnology
#18
of 134 outputs
Altmetric has tracked 24,119,703 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,034 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 303,190 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 134 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.