| Title |
Cerebral Blood Flow, Brain Tissue Oxygen, and Metabolic Effects of Decompressive Craniectomy
|
|---|---|
| Published in |
Neurocritical Care, March 2012
|
| DOI | 10.1007/s12028-012-9685-1 |
| Pubmed ID | |
| Authors |
Christos Lazaridis, Marek Czosnyka |
| Abstract |
Decompressive craniectomy (DC) is used for patients with traumatic brain injury (TBI), malignant edema from middle cerebral artery infarction, aneurysmal subarachnoid hemorrhage, and non-traumatic intracerebral or cerebellar hemorrhage. The objective of the procedure is to relieve intractable intracranial hypertension and/or to prevent or reverse cerebral herniation. Decompressive craniectomy has been shown to decrease mortality in selected patients with large hemispheric infarction and to control intracranial pressure in addition to improving pressure-volume compensatory reserve after TBI. The clinical effectiveness of DC in patients with TBI is under evaluation in ongoing randomized clinical trials. There are several unresolved controversies regarding optimal candidate selection, timing, technique, and post-operative management and complications. The nature and temporal progression of alterations in cerebral blood flow, brain tissue oxygen, and microdialysis markers have only recently been researched. Elucidating the pathophysiology of pressure-flow and cerebral hemodynamic consequences of DC could assist in optimizing clinical decision making and further defining the role of decompressive craniectomy. |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| United States | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 113 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 24 | 21% |
| Other | 21 | 18% |
| Student > Doctoral Student | 14 | 12% |
| Student > Master | 12 | 10% |
| Student > Postgraduate | 10 | 9% |
| Other | 23 | 20% |
| Unknown | 12 | 10% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 69 | 59% |
| Neuroscience | 15 | 13% |
| Engineering | 4 | 3% |
| Psychology | 3 | 3% |
| Unspecified | 2 | 2% |
| Other | 6 | 5% |
| Unknown | 17 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2012.
All research outputs
#20,156,199
of 22,664,267 outputs
Outputs from Neurocritical Care
#1,387
of 1,488 outputs
Outputs of similar age
#141,471
of 156,173 outputs
Outputs of similar age from Neurocritical Care
#8
of 8 outputs
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So far Altmetric has tracked 1,488 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one.