Title |
International field testing of the psychometric properties of an EORTC quality of life module for oral health: the EORTC QLQ-OH15
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Published in |
Supportive Care in Cancer, April 2016
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DOI | 10.1007/s00520-016-3216-0 |
Pubmed ID | |
Authors |
Marianne J. Hjermstad, Mia Bergenmar, Kristin Bjordal, Sheila E. Fisher, Dirk Hofmeister, Sébastien Montel, Ourania Nicolatou-Galitis, Monica Pinto, Judith Raber-Durlacher, Susanne Singer, Iwona M. Tomaszewska, Krzysztof A. Tomaszewski, Irma Verdonck-de Leeuw, Noam Yarom, Julie B Winstanley, Bente B. Herlofson, on behalf of the EORTC QoL Group |
Abstract |
This international EORTC validation study (phase IV) is aimed at testing the psychometric properties of a quality of life (QoL) module related to oral health problems in cancer patients. The phase III module comprised 17 items with four hypothesized multi-item scales and three single items. In phase IV, patients with mixed cancers, in different treatment phases from 10 countries completed the EORTC QLQ-C30, the QLQ-OH module, and a debriefing interview. The hypothesized structure was tested using combinations of classical test theory and item response theory, following EORTC guidelines. Test-retest assessments and responsiveness to change analysis (RCA) were performed after 2 weeks. Five hundred seventy-two patients (median age 60.3, 54 % females) were analyzed. Completion took <10 min for 84 %, 40 % expressed satisfaction that these issues were addressed. Analyses suggested a revision of the phase III hypothesized scale structure. Two items were deleted based on a high degree of item misfit, together with negative patient feedback. The remaining 15 items formed one eight-item scale named OH-QoL score, a two-item information scale, a two-item scale regarding dentures, and three single items (sticky saliva/mouth soreness/sensitivity to food/drink). Face and convergent validity and internal consistency were confirmed. Test-retest reliability (n = 60) was demonstrated as was RCA for patients undergoing chemotherapy (n = 117; p = 0.06). The resulting QLQ-OH15 discriminated between clinically distinct patient groups, e.g., low performance status vs. higher (p < 000.1), and head-and-neck cancer versus other cancers (p < 0.03). The EORTC module QLQ-OH15 is a short, well-accepted assessment tool focusing on oral problems and QoL to improve clinical management. ClinicalTrials.gov Identifier: NCT01724333. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Sweden | 1 | <1% |
Unknown | 127 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 16 | 13% |
Student > Ph. D. Student | 14 | 11% |
Researcher | 10 | 8% |
Student > Bachelor | 9 | 7% |
Student > Doctoral Student | 8 | 6% |
Other | 24 | 19% |
Unknown | 47 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 36 | 28% |
Nursing and Health Professions | 13 | 10% |
Agricultural and Biological Sciences | 7 | 5% |
Psychology | 5 | 4% |
Engineering | 3 | 2% |
Other | 16 | 13% |
Unknown | 48 | 38% |