Title |
Comparison of Corneal and Aqueous Humor Penetration of Moxifloxacin, Gatifloxacin and Levofloxacin during Keratoplasty
|
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Published in |
Advances in Therapy, April 2012
|
DOI | 10.1007/s12325-012-0016-x |
Pubmed ID | |
Authors |
Masahiko Fukuda, Masakazu Yamada, Shigeru Kinoshita, Tsutomu Inatomi, Yuichi Ohashi, Toshihiko Uno, Jun Shimazaki, Yoshiyuki Satake, Naoyuki Maeda, Yuichi Hori, Kohji Nishida, Akira Kubota, Toru Nakazawa, Yoshikazu Shimomura |
Abstract |
Achieving high antibiotic concentrations is important for preventing and treating postoperative infections. However, no study has simultaneously compared the achieved concentrations of moxifloxacin, gatifloxacin, and levofloxacin in the human cornea and aqueous humor. The authors therefore performed a randomized study to determine the concentrations of 0.5% moxifloxacin, 0.3% gatifloxacin, and 0.5% levofloxacin in the corneal tissue and aqueous humor after topical instillation in patients undergoing penetrating keratoplasty. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Turkey | 1 | 4% |
Unknown | 27 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 21% |
Student > Bachelor | 4 | 14% |
Other | 4 | 14% |
Student > Postgraduate | 3 | 11% |
Student > Ph. D. Student | 2 | 7% |
Other | 4 | 14% |
Unknown | 5 | 18% |
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Pharmacology, Toxicology and Pharmaceutical Science | 2 | 7% |
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Psychology | 1 | 4% |
Engineering | 1 | 4% |
Other | 0 | 0% |
Unknown | 7 | 25% |