| Title |
Clinical characteristics associated with the prescribing of SSRI medication in adolescents with major unipolar depression
|
|---|---|
| Published in |
European Child & Adolescent Psychiatry, April 2016
|
| DOI | 10.1007/s00787-016-0849-y |
| Pubmed ID | |
| Authors |
Lesley Cousins, Kirstie J. Whitaker, Barry Widmer, Nick Midgley, Sarah Byford, Bernadka Dubicka, Raphael Kelvin, Shirley Reynolds, Christopher Roberts, Fiona Holland, Barbara Barrett, Robert Senior, Paul Wilkinson, Mary Target, Peter Fonagy, Ian M Goodyer |
| Abstract |
Unipolar major depressions (MD) emerge markedly during adolescence. National Institute for Health and Care Excellence (NICE) UK recommends psychological therapies, with accompanying selective serotonin reuptake inhibitors (SSRIs) prescribed in severe cases only. Here, we seek to determine the extent and rationale of SSRI prescribing in adolescent MD before entering a randomised clinical trial. SSRI prescribing, together with their clinical characteristics was determined in 465 adolescent patients with MD prior to receiving a standardised psychological therapy as part of the Improving mood with psychoanalytic and cognitive therapies (IMPACT) clinical trial. Overall, 88 (19 %) had been prescribed antidepressants prior to psychological treatment. The clinical correlates varied by gender: respectively, depression severity in boys and self-harming behaviours in girls. Prescribing also differed between clinical research centres. Medical practitioners consider severity of depression in boys as an indicator for antidepressant prescribing. Self-injury in girls appears to be utilised as a prescribing aid which is inconsistent with past and current revised UK NICE guidelines. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 42% |
| Unknown | 7 | 58% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 42% |
| Scientists | 4 | 33% |
| Practitioners (doctors, other healthcare professionals) | 2 | 17% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 153 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Colombia | 1 | <1% |
| Norway | 1 | <1% |
| Unknown | 150 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 26 | 17% |
| Student > Bachelor | 21 | 14% |
| Researcher | 20 | 13% |
| Student > Ph. D. Student | 15 | 10% |
| Student > Doctoral Student | 7 | 5% |
| Other | 27 | 18% |
| Unknown | 37 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 47 | 31% |
| Medicine and Dentistry | 23 | 15% |
| Social Sciences | 11 | 7% |
| Nursing and Health Professions | 9 | 6% |
| Neuroscience | 4 | 3% |
| Other | 13 | 8% |
| Unknown | 46 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 February 2017.
All research outputs
#4,663,104
of 23,671,454 outputs
Outputs from European Child & Adolescent Psychiatry
#499
of 1,719 outputs
Outputs of similar age
#71,362
of 300,590 outputs
Outputs of similar age from European Child & Adolescent Psychiatry
#6
of 31 outputs
Altmetric has tracked 23,671,454 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.2. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 300,590 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.