| Title |
Effectiveness of Integrative Medicine Therapy on Coronary Artery Disease Prognosis: A Real-World Study
|
|---|---|
| Published in |
Chinese Journal of Integrative Medicine, April 2016
|
| DOI | 10.1007/s11655-016-2454-9 |
| Pubmed ID | |
| Authors |
Kang Zhao, Jin-fan Tian, Cong Zhao, Fei Yuan, Zhu-ye Gao, Li-zhi Li, Hong-xu Liu, Xian Wang, Chang-jiang Ge, Shu-zheng Lu |
| Abstract |
To evaluate the effectiveness of integrative medicine (IM) on patients with coronary artery disease (CAD) and investigate the prognostic factors of CAD in a real-world setting. A total of 1,087 hospitalized patients with CAD from four hospitals in Beijing, China were consecutively selected between August 2011 and February 2012. The patients were assigned to two groups based on the treatment: Chinese medicine (CM) plus conventional treatment, i.e., IM therapy (IM group); or conventional treatment alone (CT group). The endpoint was major adverse cardiac events [MACE; including cardiac death, myocardial infarction (MI), and revascularization]. A total of 1,040 patients finished the 2-year follow-up. Of them, 49.4% (514/1,040) received IM therapy. During the 2-year follow-up, the total incidence of MACE was 11.3%. Most of the events involved revascularization (9.3%). Cardiac death/MI occurred in 3.0% of cases. For revascularization, logistic stepwise regression analysis revealed that age ≥ 65 years [odds ratio (OR), 2.224], MI (OR, 2.561), diabetes mellitus (OR, 1.650), multi-vessel lesions (OR, 2.554), baseline high sensitivity C-reactive protein level ≥ 3 mg/L (OR, 1.678), and moderate or severe anxiety/depression (OR, 1.849) were negative predictors (P<0.05); while anti-platelet agents (OR, 0.422), β-blockers (OR, 0.626), statins (OR, 0.318), and IM therapy (OR, 0.583) were protective predictors (P<0.05). For cardiac death/MI, age ≥ 65 years (OR, 6.389) and heart failure (OR, 7.969) were negative predictors (P<0.05), while statin use (OR, 0.323) was a protective predictor (P<0.05) and IM therapy showed a benefifi cial tendency (OR, 0.587), although the difference was not statistically signififi cant (P=0.218). In a real-world setting, for patients with CAD, IM therapy was associated with a decreased incidence of revascularization and showed a potential benefifi t in reducing the incidence of cardiac death or MI. |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 44 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 16% |
| Student > Bachelor | 6 | 14% |
| Student > Ph. D. Student | 6 | 14% |
| Other | 4 | 9% |
| Student > Postgraduate | 4 | 9% |
| Other | 8 | 18% |
| Unknown | 9 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 15 | 34% |
| Psychology | 6 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 7% |
| Biochemistry, Genetics and Molecular Biology | 2 | 5% |
| Neuroscience | 2 | 5% |
| Other | 5 | 11% |
| Unknown | 11 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 January 2019.
All research outputs
#3,649,884
of 22,867,327 outputs
Outputs from Chinese Journal of Integrative Medicine
#65
of 677 outputs
Outputs of similar age
#58,009
of 299,116 outputs
Outputs of similar age from Chinese Journal of Integrative Medicine
#1
of 14 outputs
Altmetric has tracked 22,867,327 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 677 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 89% of its peers.
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We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.