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HCV: The Journey from Discovery to a Cure

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Cover of 'HCV: The Journey from Discovery to a Cure'

Table of Contents

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    Book Overview
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    Chapter 33 From B to Non-B to C: The Hepatitis C Virus in Historical Perspective
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    Chapter 34 The Hepatitis C Virus Replicon System and Its Role in Drug Development
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    Chapter 35 Evolution of HCV NS5B Non-nucleoside Inhibitors
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    Chapter 36 Evolution of HCV NS5B Nucleoside and Nucleotide Inhibitors
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    Chapter 37 The Discovery of Sofosbuvir: A Liver-Targeted Nucleotide Prodrug for the Treatment and Cure of HCV
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    Chapter 38 Discovery of Beclabuvir: A Potent Allosteric Inhibitor of the Hepatitis C Virus Polymerase
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    Chapter 39 Evolution of HCV NS3/4a Protease Inhibitors
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    Chapter 40 Discovery of Boceprevir, a Ketoamide-Derived HCV NS3 Protease Inhibitor, for Treatment of Genotype 1 Infections
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    Chapter 41 The Invention of Grazoprevir: An HCV NS3/4a Protease Inhibitor
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    Chapter 42 The Discovery and Development of HCV NS3 Protease Inhibitor Paritaprevir
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    Chapter 51 HCV Molecular Virology and Animal Models
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    Chapter 53 The Discovery of the Hepatitis C Virus
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    Chapter 55 Discovery and Development of the Next-Generation HCV NS3 Protease Inhibitor Glecaprevir
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    Chapter 57 Development and Marketing of INCIVEK (Telaprevir; VX-950): A First-Generation HCV Protease Inhibitor, in Combination with PEGylated Interferon and Ribavirin
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    Chapter 58 The Discovery and Early Clinical Evaluation of the HCV NS3/4A Protease Inhibitor Asunaprevir (BMS-650032)
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    Chapter 59 The Role of Interferon for the Treatment of Chronic Hepatitis C Virus Infection
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    Chapter 61 Discovery of Voxilaprevir (GS-9857): The Pan-Genotypic Hepatitis C Virus NS3/4A Protease Inhibitor Utilized as a Component of Vosevi ®
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Title
HCV: The Journey from Discovery to a Cure
Published by
Springer International Publishing, January 2020
DOI 10.1007/978-3-030-28207-3
ISBNs
978-3-03-028206-6, 978-3-03-028207-3
Editors

Sofia, Michael J.

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X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 11 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 11 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 3 27%
Student > Bachelor 2 18%
Lecturer > Senior Lecturer 1 9%
Researcher 1 9%
Student > Ph. D. Student 1 9%
Other 0 0%
Unknown 3 27%
Readers by discipline Count As %
Chemistry 3 27%
Biochemistry, Genetics and Molecular Biology 2 18%
Nursing and Health Professions 2 18%
Medicine and Dentistry 1 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 9%
Other 0 0%
Unknown 2 18%