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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Silica Nanopollens Enhance Adhesion for Long-Term Bacterial Inhibition
|
|---|---|
| Published in |
Journal of the American Chemical Society, May 2016
|
| DOI | 10.1021/jacs.6b00243 |
| Pubmed ID | |
| Authors |
Hao Song, Yusilawati Ahmad Nor, Meihua Yu, Yannan Yang, Jun Zhang, Hongwei Zhang, Chun Xu, Neena Mitter, Chengzhong Yu |
| Abstract |
Nature creations with spiky topological features typically exhibit intriguing surface adhesive property. From micrometre-sized pollen grains that can easily stick to hairy insects for pollination to nanoscale virus particles that are highly infectious towards host cells, multivalent interactions are formed taking advantages of rough surfaces. Herein, this nature-inspired concept is employed to develop novel drug delivery nano-carriers for antimicrobial applications. A facile new approach is developed to fabricate silica nano-pollens (mesoporous silica nanospheres with rough surfaces), which show enhanced adhesion towards bacteria surface comparing to their counterparts with smooth surfaces. Lysozyme, a natural antimicrobial enzyme, is loaded into silica nano-pollens, showing sustained release behavior, potent antimicrobial activity and long-term total bacterial inhibition up to 3 days towards Escherichia coli. The potent antibacterial activity of lysozyme loaded silica nano-pollens is further demonstrated ex vivo by using a small intestine infection model. Our strategy provides a novel pathway in the rational design of nano-carriers for efficient drug delivery. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 110 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 30% |
| Researcher | 16 | 15% |
| Student > Master | 15 | 14% |
| Student > Bachelor | 10 | 9% |
| Professor > Associate Professor | 6 | 5% |
| Other | 10 | 9% |
| Unknown | 20 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 29 | 26% |
| Materials Science | 16 | 15% |
| Biochemistry, Genetics and Molecular Biology | 10 | 9% |
| Engineering | 8 | 7% |
| Agricultural and Biological Sciences | 7 | 6% |
| Other | 15 | 14% |
| Unknown | 25 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2021.
All research outputs
#1,774,900
of 22,867,327 outputs
Outputs from Journal of the American Chemical Society
#3,628
of 62,071 outputs
Outputs of similar age
#32,025
of 312,362 outputs
Outputs of similar age from Journal of the American Chemical Society
#45
of 435 outputs
Altmetric has tracked 22,867,327 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 62,071 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,362 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 435 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.