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OrfM: a fast open reading frame predictor for metagenomic data

Overview of attention for article published in Bioinformatics, May 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

blogs
2 blogs
twitter
19 X users
facebook
1 Facebook page

Citations

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33 Dimensions

Readers on

mendeley
116 Mendeley
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3 CiteULike
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Title
OrfM: a fast open reading frame predictor for metagenomic data
Published in
Bioinformatics, May 2016
DOI 10.1093/bioinformatics/btw241
Pubmed ID
Authors

Ben J Woodcroft, Joel A Boyd, Gene W Tyson

Abstract

Finding and translating stretches of DNA lacking stop codons is a task common in the analysis of sequence data. However the computational tools for finding open reading frames are sufficiently slow that they are becoming a bottleneck as the volume of sequence data grows. This computational bottleneck is especially problematic in metagenomics when searching unassembled reads, or screening assembled contigs for genes of interest. Here we present OrfM, a tool to rapidly identify open reading frames (ORFs) in sequence data by applying the Aho-Corasick algorithm to find regions uninterrupted by stop codons. Benchmarking revealed that OrfM finds identical ORFs to similar tools ('GetOrf' and 'Translate') but is five times faster. While OrfM is sequencing platform-agnostic, it is best suited to large, high quality datasets such as those produced by Illumina sequencers. Source code and binaries freely available for download at http://github.com/wwood/OrfM or through GNU Guix under the LGPL 3+ license, implemented in C and supported on GNU/Linux and OSX. [email protected]; [email protected] SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.

X Demographics

X Demographics

The data shown below were collected from the profiles of 19 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 2%
Australia 1 <1%
Norway 1 <1%
Sweden 1 <1%
Canada 1 <1%
New Zealand 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 107 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 25%
Researcher 20 17%
Student > Master 20 17%
Student > Bachelor 10 9%
Student > Doctoral Student 7 6%
Other 14 12%
Unknown 16 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 30%
Biochemistry, Genetics and Molecular Biology 33 28%
Environmental Science 7 6%
Computer Science 6 5%
Immunology and Microbiology 5 4%
Other 13 11%
Unknown 17 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 January 2023.
All research outputs
#1,648,313
of 25,374,647 outputs
Outputs from Bioinformatics
#845
of 12,808 outputs
Outputs of similar age
#26,910
of 312,398 outputs
Outputs of similar age from Bioinformatics
#29
of 217 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,808 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.0. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,398 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 217 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.