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Epigenetic changes of CDX2 in gastric adenocarcinoma

Overview of attention for article published in Journal of Cell Communication and Signaling, May 2016
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Title
Epigenetic changes of CDX2 in gastric adenocarcinoma
Published in
Journal of Cell Communication and Signaling, May 2016
DOI 10.1007/s12079-016-0327-9
Pubmed ID
Authors

Ali Akbar Samadani, Novin Nikbakhsh, Maryam Pilehchian, Sadegh Fattahi, Haleh Akhavan‐Niaki

Abstract

Gastric cancer is one of the most commonplace and lethal cancers in the world. Molecular investigation of this disease, in order to obtain diagnostic and treatments achievements is important and vital. Relatively, in this research study, one of the most important epigenetic factors, the methylation of CDX2 gene was investigated in tumoral and non-tumoral tissues of gastric cancer patients by bisulfite treatment followed by sequencing of the 5'UTR region of CDX2 in both tissues. The results indicated a hypomethylation in tumoral tissues of adenocarcinoma. Consequently, the methylation amount of CDX2 in tumoral tissues was significantly reduced compared with non-tumoral tissues.

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Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 2 25%
Student > Postgraduate 2 25%
Student > Ph. D. Student 1 13%
Professor > Associate Professor 1 13%
Unknown 2 25%
Readers by discipline Count As %
Medicine and Dentistry 4 50%
Agricultural and Biological Sciences 1 13%
Biochemistry, Genetics and Molecular Biology 1 13%
Unknown 2 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2016.
All research outputs
#20,323,943
of 22,867,327 outputs
Outputs from Journal of Cell Communication and Signaling
#208
of 267 outputs
Outputs of similar age
#252,790
of 298,446 outputs
Outputs of similar age from Journal of Cell Communication and Signaling
#6
of 8 outputs
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So far Altmetric has tracked 267 research outputs from this source. They receive a mean Attention Score of 2.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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