You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7
|
|---|---|
| Published in |
Protein Science, May 2016
|
| DOI | 10.1002/pro.2943 |
| Pubmed ID | |
| Authors |
Jason W Schmidberger, Mehdi Sharifi Tabar, Mario Torrado, Ana P G Silva, Michael J Landsberg, Lou Brillault, Saad AlQarni, Yi Cheng Zeng, Benjamin L Parker, Jason K K Low, Joel P Mackay |
| Abstract |
The Nucleosome Remodeling and Deacetylase (NuRD) complex remodels the genome in the context of both gene transcription and DNA damage repair. It is essential for normal development and is distributed across multiple tissues in organisms ranging from mammals to nematode worms. In common with other chromatin-remodeling complexes, however, its molecular mechanism of action is not well understood and only limited structural information is available to show how the complex is assembled. As a step towards understanding the structure of the NuRD complex, we have characterized the interaction between two subunits: the metastasis associated protein MTA1 and the histone-binding protein RBBP4. We show that MTA1 can bind to two molecules of RBBP4 and present negative stain electron microscopy and chemical crosslinking data that allow us to build a low-resolution model of an MTA1-(RBBP4)2 subcomplex. These data build on our understanding of NuRD complex structure and move us closer towards an understanding of the biochemical basis for the activity of this complex. This article is protected by copyright. All rights reserved. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 5% |
| Denmark | 1 | 1% |
| Unknown | 79 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 31% |
| Researcher | 20 | 24% |
| Student > Master | 10 | 12% |
| Student > Bachelor | 8 | 10% |
| Professor | 7 | 8% |
| Other | 10 | 12% |
| Unknown | 3 | 4% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 32 | 38% |
| Agricultural and Biological Sciences | 22 | 26% |
| Chemistry | 9 | 11% |
| Computer Science | 4 | 5% |
| Medicine and Dentistry | 3 | 4% |
| Other | 8 | 10% |
| Unknown | 6 | 7% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2016.
All research outputs
#14,647,905
of 24,565,648 outputs
Outputs from Protein Science
#2,726
of 3,710 outputs
Outputs of similar age
#180,900
of 340,472 outputs
Outputs of similar age from Protein Science
#13
of 32 outputs
Altmetric has tracked 24,565,648 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,710 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 340,472 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.