Title |
Optical imaging of bacterial infections
|
---|---|
Published in |
Clinical and Translational Imaging, May 2016
|
DOI | 10.1007/s40336-016-0180-0 |
Pubmed ID | |
Authors |
Bethany Mills, Mark Bradley, Kevin Dhaliwal |
Abstract |
The rise in multidrug resistant (MDR) bacteria has become a global crisis. Rapid and accurate diagnosis of infection will facilitate antibiotic stewardship and preserve our ability to treat and cure patients from bacterial infection. Direct in situ imaging of bacteria offers the prospect of accurately diagnosing disease and monitoring patient outcomes and response to treatment in real-time. There have been many recent advances in the field of optical imaging of infection; namely in specific probe and fluorophore design. This combined with the advances in imaging device technology render direct optical imaging of infection a feasible approach for accurate diagnosis in the clinic. Despite this, there are currently no licensed molecular probes for clinical optical imaging of infection. Here we report some of the most promising and interesting probes and approaches under development for this purpose, which have been evaluated in in vivo models within the laboratory setting. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 6 | 55% |
Ireland | 1 | 9% |
Namibia | 1 | 9% |
Unknown | 3 | 27% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 45% |
Scientists | 5 | 45% |
Practitioners (doctors, other healthcare professionals) | 1 | 9% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 89 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 19% |
Student > Master | 13 | 15% |
Researcher | 13 | 15% |
Student > Bachelor | 7 | 8% |
Other | 6 | 7% |
Other | 11 | 12% |
Unknown | 22 | 25% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 15 | 17% |
Medicine and Dentistry | 14 | 16% |
Biochemistry, Genetics and Molecular Biology | 8 | 9% |
Immunology and Microbiology | 8 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 6% |
Other | 15 | 17% |
Unknown | 24 | 27% |