Title |
Essential oil poisoning: N-acetylcysteine for eugenol-induced hepatic failure and analysis of a national database
|
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Published in |
European Journal of Pediatrics, May 2005
|
DOI | 10.1007/s00431-005-1692-1 |
Pubmed ID | |
Authors |
Simon E. J. Janes, Caroline S. G. Price, David Thomas |
Abstract |
We present a 15-month-old boy who developed fulminant hepatic failure after ingesting 10 ml of clove oil. After 24 h, the ALT level was in excess of 13,000 U/l, with blood urea and creatinine of 11.8 mmol and 134 micromol/l respectively. The hepatic impairment resolved after intravenous administration of N-acetylcysteine so that 6 h later, the ALT level was approximately 10,000 U/l. His liver synthetic function and clinical status improved over the next 4 days. This is the first such case report of its kind in Europe. Analysis of a national database revealed a 14-fold increase in home accidents related to aromatherapy from 1994-1999. Clove oil has important hepatotoxic effects. |
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Saudi Arabia | 4 | 67% |
Unknown | 2 | 33% |
Demographic breakdown
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Mendeley readers
Geographical breakdown
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Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 10 | 19% |
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Researcher | 5 | 9% |
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