| Title |
Resistance to HIV Infection
|
|---|---|
| Published in |
Journal of Urban Health, February 2006
|
| DOI | 10.1007/s11524-005-9003-8 |
| Pubmed ID | |
| Authors |
M. Marmor, K. Hertzmark, S. M. Thomas, P. N. Halkitis, M. Vogler |
| Abstract |
The biological correlates of an effective immune response that could contain or prevent HIV infection remain elusive despite substantial scientific accomplishments in understanding the interactions among the virus, the individual and the community. The observation that some individuals appear to possess resistance to HIV infection or its consequences has generated a host of epidemiologic investigations to identify biological or behavioral characteristics of these individuals. These data might hold the keys to developing appropriate strategies for mimicking the effective responses of those who appear immune. In this paper we review genetic mechanisms including the role of chemokines and their receptors, cytokines, host genetic immune response to HIV infection, local immune response correlating with behavioral variables, co-infection and immune based mechanisms that have been elucidated so far. We offer suggestions for how to use these observations as platforms for future research to further understand natural resistance to HIV infection through cohort studies, population genotype sampling, mathematical modeling of virus-host interactions and behavioral analyses. |
X Demographics
The data shown below were collected from the profiles of 16 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 19% |
| South Africa | 3 | 19% |
| Mexico | 2 | 13% |
| Côte d'Ivoire | 1 | 6% |
| Italy | 1 | 6% |
| Unknown | 6 | 38% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 15 | 94% |
| Scientists | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| Brazil | 1 | <1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 152 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 48 | 30% |
| Student > Master | 32 | 20% |
| Student > Ph. D. Student | 18 | 11% |
| Researcher | 12 | 8% |
| Student > Doctoral Student | 7 | 4% |
| Other | 20 | 13% |
| Unknown | 21 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 23% |
| Agricultural and Biological Sciences | 33 | 21% |
| Biochemistry, Genetics and Molecular Biology | 32 | 20% |
| Immunology and Microbiology | 9 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
| Other | 16 | 10% |
| Unknown | 25 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 60. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2023.
All research outputs
#687,940
of 24,938,276 outputs
Outputs from Journal of Urban Health
#105
of 1,367 outputs
Outputs of similar age
#1,461
of 167,439 outputs
Outputs of similar age from Journal of Urban Health
#2
of 15 outputs
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So far Altmetric has tracked 1,367 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.8. This one has done particularly well, scoring higher than 92% of its peers.
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We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.