Title |
Spherical harmonic analysis of cortical complexity in autism and dyslexia
|
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Published in |
Translational Neuroscience, March 2012
|
DOI | 10.2478/s13380-012-0008-y |
Pubmed ID | |
Authors |
Emily Williams, Ayman El-Baz, Matthew Nitzken, Andrew Switala, Manuel Casanova |
Abstract |
Alterations in gyral form and complexity have been consistently noted in both autism and dyslexia. In this present study, we apply spherical harmonics, an established technique which we have exapted to estimate surface complexity of the brain, in order to identify abnormalities in gyrification between autistics, dyslexics, and controls. On the order of absolute surface complexity, autism exhibits the most extreme phenotype, controls occupy the intermediate ranges, and dyslexics exhibit lesser surface complexity. Here, we synthesize our findings which demarcate these three groups and review how factors controlling neocortical proliferation and neuronal migration may lead to these distinctive phenotypes. |
X Demographics
Geographical breakdown
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Canada | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 3% |
Netherlands | 1 | 3% |
Unknown | 37 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 23% |
Student > Ph. D. Student | 8 | 21% |
Lecturer | 3 | 8% |
Student > Bachelor | 3 | 8% |
Professor | 3 | 8% |
Other | 3 | 8% |
Unknown | 10 | 26% |
Readers by discipline | Count | As % |
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Neuroscience | 6 | 15% |
Medicine and Dentistry | 5 | 13% |
Agricultural and Biological Sciences | 4 | 10% |
Psychology | 4 | 10% |
Engineering | 3 | 8% |
Other | 6 | 15% |
Unknown | 11 | 28% |