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Attention Score in Context
| Title |
Leptin serum concentrations are associated with weight gain during lithium augmentation
|
|---|---|
| Published in |
Psychoneuroendocrinology, May 2016
|
| DOI | 10.1016/j.psyneuen.2016.04.013 |
| Pubmed ID | |
| Authors |
Roland Ricken, Sandra Bopp, Peter Schlattmann, Hubertus Himmerich, Tom Bschor, Christoph Richter, Thomas J. Stamm, Frank Bauer, Andreas Heinz, Rainer Hellweg, Undine E. Lang, Mazda Adli |
| Abstract |
Meta-analytical data show lithium augmentation (LA) as an effective treatment strategy in major depression. Weight-gain is a common side effect of LA. The proteohormone leptin is discussed to be involved in the pathophysiology of weight gain induced by psychopharmacological treatment. The purpose of our study was to investigate the association of leptin and body mass index (BMI) during LA in a prospective cohort study. Leptin serum concentrations and body mass index (BMI) were measured in a total of 89 acute depressive patients before and then after four weeks of LA. In a linear mixed model analysis the following variables had a significant positive effect on BMI: time (equal with "treatment effect of LA"; F1.83=6.05; p=0.016) and leptin (F1.111=13.83; p=0.0003) as well as the covariates male gender (F1.89=5.08; p=0.027) and adiposity (F1.85=105.13; p<0.0001). If the reported effect of leptin on BMI is specific to LA remains unclear without a control group. Leptin signalling might be involved in lithium-induced weight-gain. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 38 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 9 | 24% |
| Student > Bachelor | 5 | 13% |
| Researcher | 4 | 11% |
| Librarian | 3 | 8% |
| Student > Ph. D. Student | 3 | 8% |
| Other | 5 | 13% |
| Unknown | 9 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 34% |
| Neuroscience | 3 | 8% |
| Psychology | 3 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
| Nursing and Health Professions | 2 | 5% |
| Other | 4 | 11% |
| Unknown | 11 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 May 2016.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Psychoneuroendocrinology
#3,465
of 3,903 outputs
Outputs of similar age
#280,746
of 323,883 outputs
Outputs of similar age from Psychoneuroendocrinology
#51
of 58 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,903 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.