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Attention Score in Context
| Title |
Critical review evaluating the pig as a model for human nutritional physiology
|
|---|---|
| Published in |
Nutrition Research Reviews, May 2016
|
| DOI | 10.1017/s0954422416000020 |
| Pubmed ID | |
| Authors |
Eugeni Roura, Sietse-Jan Koopmans, Jean-Paul Lallès, Isabelle Le Huerou-Luron, Nadia de Jager, Teun Schuurman, David Val-Laillet |
| Abstract |
The present review examines the pig as a model for physiological studies in human subjects related to nutrient sensing, appetite regulation, gut barrier function, intestinal microbiota and nutritional neuroscience. The nutrient-sensing mechanisms regarding acids (sour), carbohydrates (sweet), glutamic acid (umami) and fatty acids are conserved between humans and pigs. In contrast, pigs show limited perception of high-intensity sweeteners and NaCl and sense a wider array of amino acids than humans. Differences on bitter taste may reflect the adaptation to ecosystems. In relation to appetite regulation, plasma concentrations of cholecystokinin and glucagon-like peptide-1 are similar in pigs and humans, while peptide YY in pigs is ten to twenty times higher and ghrelin two to five times lower than in humans. Pigs are an excellent model for human studies for vagal nerve function related to the hormonal regulation of food intake. Similarly, the study of gut barrier functions reveals conserved defence mechanisms between the two species particularly in functional permeability. However, human data are scant for some of the defence systems and nutritional programming. The pig model has been valuable for studying the changes in human microbiota following nutritional interventions. In particular, the use of human flora-associated pigs is a useful model for infants, but the long-term stability of the implanted human microbiota in pigs remains to be investigated. The similarity of the pig and human brain anatomy and development is paradigmatic. Brain explorations and therapies described in pig, when compared with available human data, highlight their value in nutritional neuroscience, particularly regarding functional neuroimaging techniques. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 209 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 2 | <1% |
| Unknown | 207 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 28 | 13% |
| Student > Bachelor | 25 | 12% |
| Student > Master | 22 | 11% |
| Student > Ph. D. Student | 21 | 10% |
| Student > Doctoral Student | 11 | 5% |
| Other | 25 | 12% |
| Unknown | 77 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 20% |
| Biochemistry, Genetics and Molecular Biology | 27 | 13% |
| Veterinary Science and Veterinary Medicine | 10 | 5% |
| Medicine and Dentistry | 10 | 5% |
| Chemistry | 8 | 4% |
| Other | 36 | 17% |
| Unknown | 77 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 June 2019.
All research outputs
#6,437,589
of 22,870,727 outputs
Outputs from Nutrition Research Reviews
#208
of 370 outputs
Outputs of similar age
#95,763
of 312,377 outputs
Outputs of similar age from Nutrition Research Reviews
#3
of 6 outputs
Altmetric has tracked 22,870,727 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 370 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.5. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,377 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.