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Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition

Overview of attention for article published in Addictive Behaviors, May 2016
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  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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1 X user
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1 Wikipedia page

Citations

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15 Dimensions

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71 Mendeley
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Title
Alcohol misuse in emerging adulthood: Association of dopamine and serotonin receptor genes with impulsivity-related cognition
Published in
Addictive Behaviors, May 2016
DOI 10.1016/j.addbeh.2016.05.008
Pubmed ID
Authors

Talia E. Leamy, Jason P. Connor, Joanne Voisey, Ross McD. Young, Matthew J. Gullo

Abstract

Impulsivity predicts alcohol misuse and risk for alcohol use disorder. Cognition mediates much of this association. Genes also account for a large amount of variance in alcohol misuse, with dopamine and serotonin receptor genes of particular interest, because of their role in motivated behavior. The precise psychological mechanisms through which such genes confer risk is unclear. Trait impulsivity conveys risk for alcohol misuse by influencing two distinct domains of cognition: beliefs about the reinforcing effects of alcohol consumption (positive alcohol expectancy) and the perceived ability to resist it (drinking refusal self-efficacy). This study investigated the effect of the dopamine-related polymorphism in the DRD2/ANKK1 gene (rs1800497) and a serotonin-related polymorphism in the HTR2A gene (rs6313) on associations between impulsivity, cognition, and alcohol misuse in 120 emerging adults (18-21years). HTR2A predicted lower positive alcohol expectancy, higher refusal self-efficacy, and lower alcohol misuse. However, neither polymorphism moderated the linkages between impulsivity, cognition, and alcohol misuse. This is the first report of an association between HTR2A and alcohol-related cognition. Theoretically-driven biopsychosocial models have potential to elucidate the specific cognitive mechanisms through which distal risk factors like genes and temperament affect alcohol misuse in emerging adulthood.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Unknown 70 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 12 17%
Student > Ph. D. Student 7 10%
Researcher 7 10%
Other 4 6%
Student > Master 4 6%
Other 14 20%
Unknown 23 32%
Readers by discipline Count As %
Psychology 22 31%
Neuroscience 5 7%
Agricultural and Biological Sciences 5 7%
Medicine and Dentistry 4 6%
Engineering 2 3%
Other 5 7%
Unknown 28 39%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 April 2021.
All research outputs
#7,960,052
of 25,374,647 outputs
Outputs from Addictive Behaviors
#1,695
of 4,433 outputs
Outputs of similar age
#105,196
of 312,550 outputs
Outputs of similar age from Addictive Behaviors
#34
of 88 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 4,433 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.5. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,550 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.