↓ Skip to main content

Advances in antibiotic therapy in the critically ill

Overview of attention for article published in Critical Care, May 2016
Altmetric Badge

About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

twitter
77 X users
facebook
6 Facebook pages
googleplus
1 Google+ user

Citations

dimensions_citation
98 Dimensions

Readers on

mendeley
380 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Advances in antibiotic therapy in the critically ill
Published in
Critical Care, May 2016
DOI 10.1186/s13054-016-1285-6
Pubmed ID
Authors

Jean-Louis Vincent, Matteo Bassetti, Bruno François, George Karam, Jean Chastre, Antoni Torres, Jason A. Roberts, Fabio S. Taccone, Jordi Rello, Thierry Calandra, Daniel De Backer, Tobias Welte, Massimo Antonelli

Abstract

Infections occur frequently in critically ill patients and their management can be challenging for various reasons, including delayed diagnosis, difficulties identifying causative microorganisms, and the high prevalence of antibiotic-resistant strains. In this review, we briefly discuss the importance of early infection diagnosis, before considering in more detail some of the key issues related to antibiotic management in these patients, including controversies surrounding use of combination or monotherapy, duration of therapy, and de-escalation. Antibiotic pharmacodynamics and pharmacokinetics, notably volumes of distribution and clearance, can be altered by critical illness and can influence dosing regimens. Dosing decisions in different subgroups of patients, e.g., the obese, are also covered. We also briefly consider ventilator-associated pneumonia and the role of inhaled antibiotics. Finally, we mention antibiotics that are currently being developed and show promise for the future.

X Demographics

X Demographics

The data shown below were collected from the profiles of 77 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 380 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 <1%
Brazil 1 <1%
South Africa 1 <1%
India 1 <1%
Czechia 1 <1%
Russia 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 371 98%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 58 15%
Researcher 49 13%
Other 45 12%
Student > Master 45 12%
Student > Ph. D. Student 30 8%
Other 95 25%
Unknown 58 15%
Readers by discipline Count As %
Medicine and Dentistry 224 59%
Pharmacology, Toxicology and Pharmaceutical Science 32 8%
Immunology and Microbiology 11 3%
Agricultural and Biological Sciences 9 2%
Biochemistry, Genetics and Molecular Biology 8 2%
Other 26 7%
Unknown 70 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 50. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2018.
All research outputs
#845,972
of 25,374,917 outputs
Outputs from Critical Care
#638
of 6,554 outputs
Outputs of similar age
#15,747
of 342,338 outputs
Outputs of similar age from Critical Care
#15
of 113 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,554 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,338 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 113 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.